Phytanic acid methyl ester (CAS 1118-77-0)

Phytanic acid methyl ester is a chemical compound derived from phytanic acid, a branched-chain fatty acid found primarily in foods such as dairy products and certain types of fish. In scientific research, phytanic acid methyl ester has been used as a substrate in studies investigating lipid metabolism, particularly the α-oxidation pathway. This pathway involves the conversion of phytanic acid to pristanic acid, a process essential for the metabolism of branched-chain fatty acids. Phytanic acid methyl ester serves as a valuable tool in elucidating the enzymatic mechanisms and regulatory factors involved in α-oxidation, providing insights into inherited metabolic disorders such as Refsum disease, where impaired α-oxidation leads to the accumulation of phytanic acid in tissues. Furthermore, phytanic acid methyl ester has been utilized in research exploring the physiological roles of phytanic acid in cellular processes such as lipid homeostasis, inflammation, and energy metabolism. Its use as a research reagent contributes to our understanding of lipid metabolism and its implications for human health and disease.