CD31/PECAM-1 Antibody (MEC7.46): sc-52714
- CD31/PECAM-1 Antibody (MEC7.46) is a rat monoclonal IgG1 provided at 100 µg/ml
- raised against polyoma middle T transformed EC line of mouse origin
- recommended for detection of mouse PECAM-1 expressed on the surface of endothelial cells of mouse origin by IP, IF and FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- See CD31/PECAM-1 (H-3): sc-376764 for CD31/PECAM-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD31/PECAM-1 Antibody (MEC7.46). This work is in progress.
QUICK LINKS
PECAM-1 Antibody (MEC7.46) is a rat monoclonal IgG1 antibody that detects PECAM-1 in mouse samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). PECAM-1, also known as CD31, is a crucial glycoprotein that plays a significant role in the regulation of leukocyte migration and angiogenesis, making it essential for maintaining vascular integrity and facilitating immune responses. This glycoprotein is predominantly located at the intercellular junctions of endothelial cells, where PECAM-1 mediates cell-cell adhesion and communication, thereby influencing the permeability of blood vessels and the transmigration of immune cells during inflammatory responses. The proper functioning of PECAM-1 is vital for normal physiological processes, as dysregulation can lead to various pathological conditions, including chronic inflammation and tumor metastasis. Anti-PECAM-1 antibody (MEC7.46) is an invaluable tool for researchers studying vascular biology, immune responses, and related diseases, providing insights into the complex interactions that govern cell adhesion and migration.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (MEC7.46) | sc-52714 | 100 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (MEC7.46) FITC | sc-52714 FITC | 100 tests in 2 ml | $330.00 |