PCDH1 Antibody (S-6): sc-81816
- PCDH1 Antibody (S-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 100 µg/ml
- raised against recombinant PCDH1 of human origin
- recommended for detection of PCDH1 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PCDH1 Antibody (S-6). This work is in progress.
PCDH1 Antibody (S-6) is a mouse monoclonal IgG1 antibody that detects protocadherin 1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). PCDH1, also known as PC42 or PCDH42, is a crucial 1,026 amino acid single-pass type I membrane protein characterized by seven cadherin domains, which are essential for mediating calcium-dependent cell-to-cell adhesion. Anti-PCDH1 antibody (S-6) targets a protein predominantly localized at cell-cell and cell-matrix boundaries, with high expression levels in brain and neuro-glial cells, highlighting a significant role in neuronal development and synapse formation. The structure of PCDH1, featuring a C-terminal cytoplasmic region, an extracellular region, and a transmembrane region, is vital for facilitating cell adhesion and promoting cell-cell interactions. PCDH1 exists in two isoforms due to alternative splicing, which may influence functional diversity and interactions within the neural environment. PCDH1 monoclonal antibody (S-6) serves as an invaluable tool for researchers investigating the intricate mechanisms of neural development and the role of protocadherins in cellular communication.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PCDH1 Antibody (S-6) | sc-81816 | 100 µg/ml | $339.00 |