Date published: 2025-12-18

1-800-457-3801

SCBT Portrait Logo
Seach Input

Paraformaldehyde-d2 (CAS 32008-59-6)

0.0(0)
Write a reviewAsk a question

Alternate Names:
Poly(oxymethylene-d2); Formaldehyde-d2 polymer
Application:
Paraformaldehyde-d2 is a labeled analog of paraformaldehyde
CAS Number:
32008-59-6
Molecular Weight:
32.04
Molecular Formula:
(CD2O)n
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Paraformaldehyde-d2 is used as a deuterated form of paraformaldehyde. It functions by cross-linking proteins and nucleic acids, thereby preserving the structural integrity of cells and tissues for subsequent analysis. At the molecular level, paraformaldehyde-d2 reacts with amino and imino groups in proteins and nucleic acids, forming methylene bridges that stabilize the macromolecular structures. Paraformaldehyde-d2′s mechanism of action involves the formation of covalent bonds between biomolecules, preventing their degradation and maintaining their spatial arrangement. In experimental applications, paraformaldehyde-d2 is utilized to immobilize and preserve biological samples for microscopy, immunohistochemistry, and other analytical techniques. Its ability to cross-link biomolecules may be useful in studying cellular and molecular structures without compromising their integrity.


Paraformaldehyde-d2 (CAS 32008-59-6) References

  1. Simultaneous determination of dimethylamphetamine and its metabolites in rat hair by gas chromatography-mass spectrometry.  |  Kikura, R., et al. 2000. J Chromatogr B Biomed Sci Appl. 741: 163-73. PMID: 10872586
  2. Quantification of protein isoforms in mesenchymal stem cells by reductive dimethylation of lysines in intact proteins.  |  She, YM., et al. 2012. Proteomics. 12: 369-79. PMID: 22144135
  3. Stable excited dication: trapping on the S1 state of formaldehyde dication after strong field ionization.  |  Singh, V., et al. 2022. Phys Chem Chem Phys. 24: 20701-20708. PMID: 35894510
  4. Gas-liquid chromatography-chemical ionization selected ion monitoring assay for glycerol formal in animal tissues.  |  VandenHeuvel, WJ., et al. 1983. J Agric Food Chem. 31: 548-53. PMID: 6886209
  5. Hair analysis for drugs of abuse. XIX. Determination of ephedrine and its homologs in rat hair and human hair.  |  Nakahara, Y. and Kikura, R. 1997. J Chromatogr B Biomed Sci Appl. 700: 83-91. PMID: 9390717
  6. Ring-chain tautomerism in 1, 3-diaza and 1, 3-oxaza heterocycles  |  Lambert, J. B., & Majchrzak, M. W. 1980. Journal of the American Chemical Society. 102(10): 3588-3591.
  7. Absolute vibronic intensities in the 1A2. rarw. 1A1 absorption spectrum of formaldehyde  |  Strickler, S. J., & Barnhart, R. J. 1982. The Journal of Physical Chemistry. 86(4): 448-455.
  8. Measurement of the secondary hydrogen-deuterium isotope effect in atom transfer reactions of the 1, 1-dideuterioallyl radical  |  Pasto, D. J., & Huang, N. Z. 1986. The Journal of Organic Chemistry. 51(3): 412-413.
  9. Far-infrared spectra and pseudorotational potential energy function of 1, 3-oxathiolane-2, 2-d2  |  Leibowitz, S. J., Laane, J., Verastegui Jr, R., & Villarreal, J. R. 1992. The Journal of Physical Chemistry. 96(22): 8817-8820.
  10. On the mechanism of the silicon-tethered reductive Pauson–Khand reaction  |  Reichwein, J. F., Iacono, S. T., & Pagenkopf, B. L. 2002. Tetrahedron. 58(19): 3813-3822.
  11. Synthesis of the perdeuterated cellulose solvents N‐methylmorpholine N‐oxide (NMMO‐d11) and N, N‐dimethylacetamide (DMAc‐d9)  |  Adelwöhrer, C., Yoneda, Y., Nakatsubo, F., & Rosenau, T. 2008. Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal of the International Isotope Society. 51(1): 28-32.
  12. Synthesis of [2H]‐and [13C]‐labeled pyronaridine tetraphosphate-an antimalarial drug. Journal of Labelled Compounds and Radiopharmaceuticals  |  Park, S. H., Jeong, Y. J., & Pradeep, K. 2009. The Official Journal of the International Isotope Society. 52(2): 56-62.
  13. Phosphine‐Catalyzed Interrupted Morita–Baylis–Hillman Reaction and Switchable Domino Reactions of α‐Substituted Activated Olefins with Formaldehyde and Mechanism Elucidation  |  Gu, J., Xiao, B. X., Ouyang, Q., Du, W., & Chen, Y. C. 2019. Chinese Journal of Chemistry. 37(2): 155-160.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Paraformaldehyde-d2, 1 g

sc-236285
1 g
$255.00