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Paraformaldehyde-d2 is used as a deuterated form of paraformaldehyde. It functions by cross-linking proteins and nucleic acids, thereby preserving the structural integrity of cells and tissues for subsequent analysis. At the molecular level, paraformaldehyde-d2 reacts with amino and imino groups in proteins and nucleic acids, forming methylene bridges that stabilize the macromolecular structures. Paraformaldehyde-d2′s mechanism of action involves the formation of covalent bonds between biomolecules, preventing their degradation and maintaining their spatial arrangement. In experimental applications, paraformaldehyde-d2 is utilized to immobilize and preserve biological samples for microscopy, immunohistochemistry, and other analytical techniques. Its ability to cross-link biomolecules may be useful in studying cellular and molecular structures without compromising their integrity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Paraformaldehyde-d2, 1 g | sc-236285 | 1 g | $255.00 |