Molecular structure of Paeoniflorin, CAS Number: 23180-57-6
Paeoniflorin (CAS 23180-57-6)
Alternate Names:
Paeonia moutan
Application:
Paeoniflorin is a glycoside that activates Adenosine A1-R
CAS Number:
23180-57-6
Purity:
≥98%
Molecular Weight:
480.46
Molecular Formula:
C23H28O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Paeoniflorin is a glycoside isolated from the root of Paeonia lactiflora. It has been used as an anticonvulsant and has hypoglycemic effect. It reverses guanethidine-induced hypotension by activating the central adenosine A1 receptors in the brain.
Paeoniflorin (CAS 23180-57-6) References
- Paeoniflorin reverses guanethidine-induced hypotension via activation of central adenosine A1 receptors in Wistar rats. | Cheng, JT., et al. 1999. Clin Exp Pharmacol Physiol. 26: 815-6. PMID: 10549407
- Paeoniflorin: an antihyperlipidemic agent from Paeonia lactiflora. | Yang, HO., et al. 2004. Fitoterapia. 75: 45-9. PMID: 14693219
- Paeoniflorin, a novel heat shock protein-inducing compound. | Yan, D., et al. 2004. Cell Stress Chaperones. 9: 378-89. PMID: 15633296
- The anti-inflammatory effect of paeoniflorin on cerebral infarction induced by ischemia-reperfusion injury in Sprague-Dawley rats. | Tang, NY., et al. 2010. Am J Chin Med. 38: 51-64. PMID: 20128044
- The antidepressant-like effects of paeoniflorin in mouse models. | Qiu, F., et al. 2013. Exp Ther Med. 5: 1113-1116. PMID: 23599734
- Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. | Zhang, J., et al. 2014. Am J Physiol Gastrointest Liver Physiol. 306: G27-36. PMID: 24232001
- The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6'-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases. | Tu, J., et al. 2019. Front Pharmacol. 10: 57. PMID: 30804784
- Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony. | Zhang, L. and Wei, W. 2020. Pharmacol Ther. 207: 107452. PMID: 31836457
- Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases-A Mini Review. | Ma, X., et al. 2020. Front Pharmacol. 11: 531. PMID: 32410996
- A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects. | Zhou, YX., et al. 2020. Biomed Pharmacother. 130: 110505. PMID: 32682112
- The multifaceted mechanisms of Paeoniflorin in the treatment of tumors: State-of-the-Art. | Wang, XZ., et al. 2022. Biomed Pharmacother. 149: 112800. PMID: 35279012
- Metabolism of paeoniflorin and related compounds by human intestinal bacteria. | Hattori, M., et al. 1985. Chem Pharm Bull (Tokyo). 33: 3838-46. PMID: 4092282
- Absorption and excretion of paeoniflorin in rats. | Takeda, S., et al. 1995. J Pharm Pharmacol. 47: 1036-40. PMID: 8932691
- Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora. | Hsu, FL., et al. 1997. Planta Med. 63: 323-5. PMID: 9270377
- Potent anticonvulsant paeonimetabolin-I derivatives obtained by incubation of paeoniflorin and thiol compounds with Lactobacillus brevis. | Abdel-Hafez, AA., et al. 1998. Chem Pharm Bull (Tokyo). 46: 1486-7. PMID: 9775444
Activator of:
Adenosine A1-R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Paeoniflorin, 1 mg | sc-204827 | 1 mg | $20.00 | |||
Paeoniflorin, 5 mg | sc-204827A | 5 mg | $61.00 | |||
Paeoniflorin, 100 mg | sc-204827B | 100 mg | $306.00 |