Molecular structure of Olaquindox, CAS Number: 23696-28-8
Olaquindox (CAS 23696-28-8)
Alternate Names:
N-(2-Hydroxyethyl)-3-methyl-2-quinoxalinecarboxamide 1,4-dioxide
Application:
Olaquindox is a growth stimulant
CAS Number:
23696-28-8
Molecular Weight:
263.25
Molecular Formula:
C12H13N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Olaquindox is a growth stimulant antibiotic. It binds to the ribosomes of bacteria, which prevents the bacteria from synthesizing proteins and other essential components. As a result, the bacteria are unable to replicate and eventually die. It also inhibits the production of toxins and enzymes, which can be beneficial in controlling the growth of certain bacteria. Olaquindox may act to be an effective antimicrobial agent against a variety of bacterial species, including E. coli, Salmonella, Staphylococcus aureus, and Pseudomonas aeruginosa, as well as against fungi like Candida albicans.
Olaquindox (CAS 23696-28-8) References
- Olaquindox-induced genotoxicity and oxidative DNA damage in human hepatoma G2 (HepG2) cells. | Zou, J., et al. 2009. Mutat Res. 676: 27-33. PMID: 19486861
- The metabolism of olaquindox in rats, chickens and pigs. | Liu, ZY., et al. 2011. Toxicol Lett. 200: 24-33. PMID: 20974235
- The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview. | Liu, ZY. and Sun, ZL. 2013. Med Chem. 9: 1017-27. PMID: 23521002
- Reactive oxygen species-dependent JNK downregulated olaquindox-induced autophagy in HepG2 cells. | Zhao, D., et al. 2015. J Appl Toxicol. 35: 709-16. PMID: 25042557
- [Research on olaquindox induced endoplasmic reticulum stress related apoptosis on nephrotoxicity]. | Li, Z., et al. 2015. Wei Sheng Yan Jiu. 44: 444-50. PMID: 26137627
- Effect of GADD45a on olaquindox-induced apoptosis in human hepatoma G2 cells: Involvement of mitochondrial dysfunction. | Li, D., et al. 2016. Environ Toxicol Pharmacol. 46: 140-146. PMID: 27458702
- GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways. | Li, D., et al. 2017. Molecules. 22: PMID: 28098804
- TCS2 Increases Olaquindox-Induced Apoptosis by Upregulation of ROS Production and Downregulation of Autophagy in HEK293 Cells. | Li, D., et al. 2017. Molecules. 22: PMID: 28387735
- Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells. | Wu, D., et al. 2017. Oncotarget. 8: 88630-88644. PMID: 29179463
- Acute and Subacute toxicity study of Olaquindox by feeding to common carp (Cyprinus carpio L.). | Yang, Q., et al. 2018. Ecotoxicol Environ Saf. 161: 342-349. PMID: 29890435
- Simultaneous determination of olaquindox, oxytetracycline and chlorotetracycline in feeds by high performance liquid chromatography with ultraviolet and fluorescence detection adopting online synchronous derivation and separation. | Han, J., et al. 2020. J Chromatogr B Analyt Technol Biomed Life Sci. 1152: 122253. PMID: 32615537
- Molecular mechanism of olaquindox-induced hepatotoxicity and the hepatic protective role of curcumin. | Li, D., et al. 2020. Food Chem Toxicol. 145: 111727. PMID: 32898599
- Developmental neurotoxicity and toxic mechanisms induced by olaquindox in zebrafish. | Guo, SY., et al. 2021. J Appl Toxicol. 41: 549-560. PMID: 33111391
- Olaquindox-Induced Liver Damage Involved the Crosstalk of Oxidative Stress and p53 In Vivo and In Vitro. | Li, D., et al. 2020. Oxid Med Cell Longev. 2020: 8835207. PMID: 33381272
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Olaquindox, 100 mg | sc-236250 | 100 mg | $86.00 |