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O-Phospho-L-serine is an L-AP4 (sc-200432) agonist and a competitive NMDA antagonist. O-Phospho-L-serine has affinity for mGluR-4 (type IV), but not type I, metabotropic glutamate group III receptor agonist (mGluR-4, mGluR-7, and mGluR-8). O-Phospho-L-serine also inhibits proliferation and enhances neuronal differentiation in progenitor cells.
1. Klunk, W E., et al., 1991. L-phosphoserine, a metabolite elevated in Alzheimer's disease, interacts with specific L-glutamate receptor subtypes. Journal of neurochemistry. 56(6): 1997-2003. PMID: 1673996
2. Thomsen, C., et al., 1993. Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor. Neuroreport. 4(9): 1099-101. PMID: 8106006
3. Borodezt, K., et al., 1998. Decreased expression of the metabotropic glutamate receptor-4 gene is associated with neuronal apoptosis. Journal of neuroscience research. 53(5): 531-41. PMID: 9726424
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