NTF2 Antibody (5A3): sc-80008

NTF2 Antibody (5A3) is a mouse monoclonal IgG2a antibody that detects NTF2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NTF2, or nuclear transport factor 2, plays a crucial role in the nuclear transport process by facilitating the import of proteins into the nucleus, which is essential for regulating various cellular functions, including gene expression and cell cycle progression. NTF2 is primarily located in the cytoplasm and the nucleus, where NTF2 binds to nucleoporins, such as p62, to form a complex that aids in the translocation of cargo proteins across the nuclear envelope. The interaction between NTF2 and nucleoporins is vital for maintaining the efficiency of nuclear transport, as this interaction ensures that proteins are correctly recognized and imported into the nucleus, thereby influencing cellular homeostasis and response to external signals. Anti-NTF2 antibody (5A3) is an invaluable tool for researchers studying nuclear transport mechanisms and their implications in cellular processes and diseases.

The preferred NTF2 antibody is NTF2 Antibody (B-7): sc-271693.