Neurokinin B (CAS 86933-75-7)

Neurokinin B is a neuropeptide belonging to the tachykinin family, like substance P and neurokinin A, and plays a significant role in neuroendocrine communication. It binds specifically to the neurokinin-3 (NK3) receptor, which is highly expressed in certain areas of the brain, including the hypothalamus. The interaction between neurokinin B and the NK3 receptor has been extensively studied to understand its function in neuroendocrine regulation and the modulation of neuroendocrine axes, particularly those involving reproductive and stress-related hormones. In scientific research, Neurokinin B is utilized to investigate its signaling pathways and its effects on neurotransmitter release, which is crucial for understanding the dynamics of neuroendocrine responses to environmental stimuli. This peptide has been instrumental in dissecting the molecular mechanisms by which neuropeptides influence the secretion of other hormones, offering insights into the integrated control of endocrine functions. Studies involving neurokinin B are particularly significant in the field of neurobiology, where understanding the specific roles of neuropeptides continues to be crucial in elucidating the complex interplay between the nervous system and endocrine responses, focusing entirely on biochemical and physiological research.