NCAM/CD56 (h): 293T Lysate: sc-115782

NCAM (h): 293T Lysate, derived from the HEK 293T cell line, is a crucial tool for studying Neural Cell Adhesion Molecule (NCAM), a protein that plays a significant role in cell-cell adhesion, neurite outgrowth, and synaptic plasticity. The HEK 293T cells, a variant of the original HEK 293 cells modified to express the SV40 large T antigen, enhance protein production capabilities, making them ideal for producing lysates rich in NCAM. This lysate is extensively used to explore the molecular mechanisms by which NCAM mediates its effects on neural development and cellular interactions. Researchers utilize NCAM (h): 293T Lysate to investigate how NCAM interacts with other cell surface molecules and intracellular signaling pathways. NCAM is known to engage in homophilic binding and interact with the fibroblast growth factor receptor (FGFR) to activate downstream signaling cascades such as the MAPK/ERK pathway. Techniques like immunoprecipitation, Western blotting, and immunofluorescence are commonly employed to study these interactions and to explain the role of NCAM in promoting neurite outgrowth and synaptic plasticity. This lysate facilitates the detailed analysis of NCAM's function in neural cell adhesion and communication, contributing to a deeper understanding of neural development and plasticity.