Date published: 2025-10-16

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N-Thionylaniline (CAS 1122-83-4)

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Alternate Names:
N-Sulfinyl-aniline
CAS Number:
1122-83-4
Purity:
98%
Molecular Weight:
139.18
Molecular Formula:
C6H5NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Thionylaniline is a chemical compound that functions as a nucleophilic aromatic substitution reagent in organic synthesis. It acts as a source of the thiolate anion, which can undergo substitution reactions with electrophilic aromatic compounds. This compound′s mode of action involves the attack of the thiolate anion on the electrophilic aromatic substrate, leading to the formation of a new carbon-sulfur bond. This reaction is used in the synthesis of various sulfur-containing organic compounds, including bioactive intermediates, agrochemicals, and materials science. In the experimental context, N-Thionylaniline serves as a reagent for the introduction of sulfur functionality into aromatic compounds, enabling the creation of varying chemical structures for further study and characterization.


N-Thionylaniline (CAS 1122-83-4) References

  1. Cp*RuCl-catalyzed [2 + 2 + 2] cycloadditions of alpha,omega-diynes with electron-deficient carbon-heteroatom multiple bonds leading to heterocycles.  |  Yamamoto, Y., et al. 2005. J Am Chem Soc. 127: 605-13. PMID: 15643884
  2. N-Hydroxy sulfonimidamides as new nitroxyl (HNO) donors.  |  Pennington, RL., et al. 2005. Bioorg Med Chem Lett. 15: 2331-4. PMID: 15837319
  3. Synthesis and characterization of a series of annelated benzotriazole based polymers with variable bandgap.  |  Tam, TL., et al. 2012. J Org Chem. 77: 10035-41. PMID: 23092430
  4. Double carbometallation of alkynes: an efficient strategy for the construction of polycycles.  |  Luo, Y., et al. 2014. Chem Soc Rev. 43: 834-46. PMID: 24280731
  5. Novel benzo-bis(1,2,5-thiadiazole) fluorophores for in vivo NIR-II imaging of cancer.  |  Sun, Y., et al. 2016. Chem Sci. 7: 6203-6207. PMID: 30034761
  6. Supramolecular Capsules: Strong versus Weak Chalcogen Bonding.  |  Riwar, LJ., et al. 2018. Angew Chem Int Ed Engl. 57: 17259-17264. PMID: 30480857
  7. Novel near-infrared II aggregation-induced emission dots for in vivo bioimaging.  |  Lin, J., et al. 2019. Chem Sci. 10: 1219-1226. PMID: 30774922
  8. SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism.  |  Benson, S., et al. 2019. Angew Chem Int Ed Engl. 58: 6911-6915. PMID: 30924239
  9. A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery.  |  Zeng, X., et al. 2019. Chem Commun (Camb). 55: 14287-14290. PMID: 31712798
  10. Novel small-molecule fluorophores for in vivo NIR-IIa and NIR-IIb imaging.  |  Li, Q., et al. 2020. Chem Commun (Camb). 56: 3289-3292. PMID: 32073036
  11. Quaternary Ammonium Salt Based NIR-II Probes for in vivo Imaging.  |  Qu, C., et al. 2019. Adv Opt Mater. 7: PMID: 32983835
  12. Synthesis and pharmacological validation of fluorescent diarylsulfonylurea analogues as NLRP3 inhibitors and imaging probes.  |  Zhao, J., et al. 2022. Eur J Med Chem. 237: 114338. PMID: 35436667
  13. Long wavelength-emissive Ru(II) metallacycle-based photosensitizer assisting in vivo bacterial diagnosis and antibacterial treatment.  |  Xu, Y., et al. 2022. Proc Natl Acad Sci U S A. 119: e2209904119. PMID: 35914164

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Thionylaniline, 25 g

sc-257870
25 g
$81.00