Molecular structure of N-Succinimidyl-S-acetylthioacetate, CAS Number: 76931-93-6
N-Succinimidyl-S-acetylthioacetate (CAS 76931-93-6)
Alternate Names:
SATA
Application:
N-Succinimidyl-S-acetylthioacetate is reacts with 1 amines to add protected thiol groups
CAS Number:
76931-93-6
Purity:
≥95%
Molecular Weight:
231.22
Molecular Formula:
C8H9NO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-Succinimidyl-S-acetylthioacetate reacts with primary amines in order to add protected sulfhydryls. N-Succinimidyl-S-acetylthioacetate (SATA) is a chemical reagent used extensively in bioconjugation chemistry for the specific modification of biomolecules, such as proteins and peptides, by introducing protected sulfhydryl groups through its reaction with primary amines. The mechanism of this reaction begins with the active ester moiety of N-Succinimidyl-S-acetylthioacetate, which is highly reactive towards nucleophilic groups, such as the primary amines present on lysine residues of proteins or the N-terminal amine of peptides. Upon reaction, N-Succinimidyl-S-acetylthioacetate transfers its S-acetylthioacetate group to the amine, forming a stable amide bond and leaving a protected sulfhydryl group in the form of an S-acetylthioethyl moiety.
N-Succinimidyl-S-acetylthioacetate (CAS 76931-93-6) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Succinimidyl-S-acetylthioacetate, 50 mg | sc-212282B | 50 mg | $95.00 | |||
N-Succinimidyl-S-acetylthioacetate, 100 mg | sc-212282A | 100 mg | $160.00 | |||
N-Succinimidyl-S-acetylthioacetate, 250 mg | sc-212282 | 250 mg | $260.00 | |||
N-Succinimidyl-S-acetylthioacetate, 1 g | sc-212282C | 1 g | $745.00 | |||
N-Succinimidyl-S-acetylthioacetate, 5 g | sc-212282D | 5 g | $3350.00 |