Molecular structure of N-Phenylphthalimide, CAS Number: 520-03-6
N-Phenylphthalimide (CAS 520-03-6)
Alternate Names:
2-Phenyl-isoindole-1,3-dione
CAS Number:
520-03-6
Purity:
≥95%
Molecular Weight:
223.23
Molecular Formula:
C14H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-Phenylphthalimide, a derivative of phthalimide, exhibits a phenyl group attached to its nitrogen atom. It finds utility in the synthesis of a diverse range of organic compounds, including amino acids, peptides, and polymers. Moreover, it serves as a precursor for the synthesis of heterocyclic compounds like thiophenes and pyrimidines. An interesting attribute of N-Phenylphthalimide is its ability to act as an inhibitor for specific enzymes, such as phosphatases and proteases. This inhibition can have implications on the metabolic pathways of proteins and other molecules.
N-Phenylphthalimide (CAS 520-03-6) References
- Novel small molecule nonpeptide aminopeptidase n inhibitors with a cyclic imide skeleton. | Shimazawa, R., et al. 1999. J Enzyme Inhib. 14: 259-75. PMID: 10445048
- Applying Tandem Mass Spectral Libraries for Solving the Critical Assessment of Small Molecule Identification (CASMI) LC/MS Challenge 2012. | Oberacher, H. 2013. Metabolites. 3: 312-24. PMID: 24957994
- Acetic acid-catalyzed formation of N-phenylphthalimide from phthalanilic acid: a computational study of the mechanism. | Takahashi, O., et al. 2015. Int J Mol Sci. 16: 12174-84. PMID: 26030675
- Biochemical and physiological mode of action of tiafenacil, a new protoporphyrinogen IX oxidase-inhibiting herbicide. | Park, J., et al. 2018. Pestic Biochem Physiol. 152: 38-44. PMID: 30497709
- N-phenyl-3-hydroxyphthalimidine: reduction of N-phenylphthalimide with sodium borohydride | Huang, S. J. 1968. Chemical Communications (London). (5): 245-245.
- Preparation of polyimides from pyromellitic dithioanhydride and aromatic diamines | Imai, Y., & Kojima, K. 1972. Journal of Polymer Science Part A‐1: Polymer Chemistry. 10(7): 2091-2096.
- Electron-acceptor properties of N, N′-arylenebisphthalimides | Pebalk, D. V., Kotov, B. V., & Pravednikov, A. N. 1983. Bulletin of the Academy of Sciences of the USSR, Division of chemical science. 32(2): 279-281.
- Photodegradation of polyimides: 4. Mechanism for the photo-oxidation process based on a model compound | Hoyle, C. E., Creed, D., Nagarajan, R., Subramanian, P., & Anzures, E. T. 1992. Polymer. 33(15): 3162-3168.
- The oxidative degradation of imide polymers. I: Ozonolysis of a model compound, N‐phenylphthalimide | Barman, S., Newhouse, E. I., & Neely, W. C. 1994. Polymer Engineering & Science. 34(4): 279-284.
- Suggested Improved Method for the Ing‐Manske and Related Reactions for the Second Step of Gabriel Synthesis of Primary Amines | Ariffin, A., Khan, M. N., Lan, L. C., May, F. Y., & Yun, C. S. 2004. Synthetic communications. 34(24): 4439-4445.
- Effects of mixed H2O‐CH3CN solvents on the rate of hydrazinolysis of N‐phenylphthalimide: Spectral and kinetic evidence for the occurrence of N‐aminophthalimide on the reaction path | Ariffin, A., Leng, S. Y., Lan, L. C., & Khan, M. N. 2005. International journal of chemical kinetics. 37(3): 147-161.
- Standard molar enthalpies of formation and sublimation of N-phenylphthalimide | Ribeiro da Silva, M. A. V., & Santos, C. P. 2007. Journal of thermal analysis and calorimetry. 87: 21-25.
- Synthesis and Crystal Structure Studies of Three N-Phenylphthalimide Derivatives | Rauf, M. K., Mushtaq, R., Badshah, A., Kingsford-Adaboh, R., Harrison, J. J. E. K., & Ishida, H. 2013. Journal of Chemical Crystallography. 43: 144-150.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Phenylphthalimide, 1 g | sc-250487A | 1 g | $43.00 | |||
N-Phenylphthalimide, 2.5 g | sc-250487B | 2.5 g | $65.00 | |||
N-Phenylphthalimide, 5 g | sc-250487 | 5 g | $117.00 | |||
N-Phenylphthalimide, 10 g | sc-250487C | 10 g | $200.00 |