Molecular structure of N-nonanoyl-L-Homoserine lactone, CAS Number: 177158-21-3
N-nonanoyl-L-Homoserine lactone (CAS 177158-21-3)
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Alternate Names:
C9-HSL
Application:
N-nonanoyl-L-Homoserine lactone is a rare odd-numbered acyl carbon chain produced by the wild-type Erwinia carotovora strain
CAS Number:
177158-21-3
Purity:
≥98%
Molecular Weight:
241.33
Molecular Formula:
C13H23NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-nonanoyl-L-Homoserine lactone is a white or slightly off-white crystalline solid that dissolves well in organic solvents like ethanol and dimethyl sulfoxide. This particular homoserine lactone is essential for bacterial communication. Additionally, it′s used to test the effectiveness of antibiotics and various antimicrobial agents when dealing with bacterial biofilms. N-nonanoyl-L-Homoserine lactone is a rare odd-numbered acyl carbon chain produced by the wild-type Erwinia carotovora strain SCC 3193 grown in the nutrient-rich Luria-Bertani Broth (LB) medium.
N-nonanoyl-L-Homoserine lactone (CAS 177158-21-3) References
- Altering substrate chain length specificity of an acylhomoserine lactone synthase in bacterial communication. | Brader, G., et al. 2005. J Biol Chem. 280: 10403-9. PMID: 15634689
- Methylobacterium extorquens AM1 produces a novel type of acyl-homoserine lactone with a double unsaturated side chain under methylotrophic growth conditions. | Nieto Penalver, CG., et al. 2006. FEBS Lett. 580: 561-7. PMID: 16412429
- The biology and future prospects of antivirulence therapies. | Cegelski, L., et al. 2008. Nat Rev Microbiol. 6: 17-27. PMID: 18079741
- Quorum sensing negatively regulates multinucleate cell formation during intracellular growth of Burkholderia pseudomallei in macrophage-like cells. | Horton, RE., et al. 2013. PLoS One. 8: e63394. PMID: 23704903
- Identification of Metabolites and Metabolic Pathways Related to Treatment with Bufei Yishen Formula in a Rat COPD Model Using HPLC Q-TOF/MS. | Yang, L., et al. 2015. Evid Based Complement Alternat Med. 2015: 956750. PMID: 26170891
- Protein-protein interaction and molecular dynamics analysis for identification of novel inhibitors in Burkholderia cepacia GG4. | Gupta, M., et al. 2016. Comput Biol Chem. 65: 80-90. PMID: 27776248
- Annotation and quantification of N-acyl homoserine lactones implied in bacterial quorum sensing by supercritical-fluid chromatography coupled with high-resolution mass spectrometry. | Hoang, TPT., et al. 2020. Anal Bioanal Chem. 412: 2261-2276. PMID: 31919609
- Detection of gut microbiota and pathogen produced N-acyl homoserine in host circulation and tissues. | Xue, J., et al. 2021. NPJ Biofilms Microbiomes. 7: 53. PMID: 34183673
- Human TRPV1 and TRPA1 are receptors for bacterial quorum sensing molecules. | Tobita, N., et al. 2022. J Biochem. 170: 775-785. PMID: 34557892
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-nonanoyl-L-Homoserine lactone, 5 mg | sc-224145 | 5 mg | $40.00 | |||
N-nonanoyl-L-Homoserine lactone, 10 mg | sc-224145A | 10 mg | $75.00 |