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N,N-Diethylnipecotamide (DNP) is an organic compound derived from nipecotic acid, known for its ability to inhibit the enzyme glutamate dehydrogenase (GDH). This small molecule has found its way into diverse scientific research applications, especially in exploring the biochemical and physiological effects of GDH inhibition. In the realm of scientific investigations, N,N-Diethylnipecotamide has been extensively employed to study the impact of GDH inhibition on amino acid metabolism and its influence on regulating energy balance. Moreover, researchers have delved into its effects on neurotransmitter release regulation and neuronal excitability. The mechanism of action for N,N-Diethylnipecotamide involves its binding to the active site of GDH, effectively blocking the enzyme′s activity. This inhibition results in an accumulation of the substrate glutamate, leading to increased levels of other neurotransmitters like aspartate and GABA.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N,N-Diethylnipecotamide, 10 g | sc-228758 | 10 g | $250.00 |