N-Myc Antibody (3C165): sc-71633
- N-Myc Antibody (3C165) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 200 µg/ml
- epitope mapping at residues 327-339 of N-Myc of human origin
- recommended for detection of N-Myc p67 of mouse, rat and human origin by WB, IP and IF
- See N-Myc (B8.4.B): sc-53993 for N-Myc antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for N-Myc Antibody (3C165). This work is in progress.
N-Myc Antibody (3C165) is a mouse monoclonal IgG2a antibody that detects N-Myc in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). N-Myc is a critical member of the Myc family of oncogenes, which play a pivotal role in cell proliferation, differentiation, and apoptosis. N-Myc is primarily located in the nucleus, where N-Myc functions as a transcription factor regulating gene expression involved in cell growth and metabolism. This nuclear localization is essential for N-Myc′s role in oncogenesis, as N-Myc interacts with various transcriptional co-factors and chromatin remodeling complexes, thereby influencing the transcription of target genes that drive tumorigenesis. Notably, aberrant expression of N-Myc is frequently associated with aggressive forms of neuroblastoma, making N-Myc a significant biomarker for this cancer type. Anti-N-Myc antibody (3C165) provides a reliable tool for researchers studying the molecular mechanisms of cancer and the functional dynamics of N-Myc.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Myc Antibody (3C165) | sc-71633 | 200 µg/ml | $322.00 |