Date published: 2025-12-7

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N-Chlorophthalimide (CAS 3481-09-2)

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CAS Number:
3481-09-2
Purity:
>95%
Molecular Weight:
181.58
Molecular Formula:
C8H4ClNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Chlorophthalimide is a chemical compound that functions as a chlorinating agent in various chemical reactions. Its mechanism of action involves the transfer of chlorine atoms to organic compounds, leading to the formation of chlorinated products. This process occurs through electrophilic aromatic substitution, where the chlorine atom is introduced into the aromatic ring of the organic substrate. N-Chlorophthalimide acts as a source of electrophilic chlorine, facilitating the chlorination of a wide range of organic molecules. Its mechanism of action involves the generation of reactive chlorine species, which can selectively chlorinate specific positions on aromatic rings, enabling the synthesis of diverse chlorinated organic molecules.


N-Chlorophthalimide (CAS 3481-09-2) References

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  6. One-pot synthesis of diverse N,N'-disubstituted guanidines from N-chlorophthalimide, isocyanides and amines via N-phthaloyl-guanidines.  |  Demjén, A., et al. 2018. Org Biomol Chem. 16: 2143-2149. PMID: 29517090
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  8. Regioselective α-Amination of Ethers Using Stable N-Chloroimides and Lithium tert-Butoxide.  |  Gasonoo, M., et al. 2019. J Org Chem. 84: 8710-8716. PMID: 31244155
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  12. Application of 1D 15 N and band-selective 2D 1 H-15 N CLIP-HSQMBC to detect 35/37 Cl isotope effect on nitrogen for unequivocal structure elucidation of the N-Cl moiety in molecules.  |  Hwang, TL., et al. 2022. Magn Reson Chem. 60: 157-164. PMID: 34376016
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Chlorophthalimide, 25 g

sc-236030
25 g
$31.00