Date published: 2026-3-13

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N-butyryl-L-Homoserine lactone-d5

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Molecular Weight:
176.2
Molecular Formula:
C8H8D5NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-butyryl-L-homoserine lactone-d5 (C4-HSL-d5) is a deuterium-labeled derivative of N-butyryl-L-homoserine lactone (C4-HSL), a key signaling molecule utilized in bacterial quorum sensing systems. Quorum sensing is a cell-to-cell communication mechanism employed by bacteria to regulate gene expression in a population density-dependent manner. C4-HSL-d5 serves as a valuable tool in elucidating the intricacies of quorum sensing due to its ability to be tracked and quantified with high precision using analytical techniques such as mass spectrometry. By incorporating deuterium atoms into its structure, C4-HSL-d5 facilitates the study of bacterial communication dynamics and the role of quorum sensing in various microbial processes. Researchers leverage C4-HSL-d5 in microbiology studies to investigate bacterial behaviors such as biofilm formation, virulence factor production, and antibiotic resistance. Furthermore, C4-HSL-d5 has been instrumental in unraveling the mechanisms underlying inter-species communication and competition in complex microbial communities, shedding light on microbial ecology and evolution. Its applications extend to environmental monitoring, biotechnology, and synthetic biology, where understanding bacterial communication networks can inform the development of novel strategies for biocontrol, bioremediation, and bioproduction processes.


N-butyryl-L-Homoserine lactone-d5 References

  1. Identification of a solo acylhomoserine lactone synthase from the myxobacterium Archangium gephyra.  |  Albataineh, H., et al. 2021. Sci Rep. 11: 3018. PMID: 33542315

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-butyryl-L-Homoserine lactone-d5, 250 µg

sc-221996
250 µg
$25.00

N-butyryl-L-Homoserine lactone-d5, 1 mg

sc-221996A
1 mg
$48.00