Date published: 2025-10-18

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Myosin Antibody (414): sc-52348

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Datasheets
  • Myosin Antibody (414) is a mouse monoclonal IgM provided at 500 µl supernatant
  • raised against skeletal muscle cell preparation of chicken origin
  • recommended for detection of Myosin of avian origin by WB, IF and IHC(P)
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Myosin Antibody (414). This work is in progress.

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    Myosin Antibody (414) is a mouse monoclonal IgM antibody that detects Myosin of avian origin by western blotting (WB), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-Myosin antibody (414) is available in non-conjugated form. Myosin plays a critical role in muscle contraction and cellular movement, functioning as a motor protein that converts chemical energy from ATP hydrolysis into mechanical work. This process is essential for various physiological functions, including muscle contraction, cell division, and intracellular transport. Myosin is composed of a hexameric structure consisting of four light chains and two heavy chains, with each heavy chain being approximately 2000 amino acids long and featuring distinct N-terminal and C-terminal domains that adopt a coiled-coil configuration. The interaction between myosin and actin filaments is fundamental to generating the force necessary for muscle contraction and other cellular movements, making anti-Myosin antibody (414) a valuable tool for studying these processes in avian tissues.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Myosin Antibody (414) References:

    1. A myosin family tree.  |  Hodge, T. and Cope, MJ. 2000. J Cell Sci. 113 Pt 19: 3353-4. PMID: 10984423
    2. Contractile protein isozymes in muscle development: identification of an embryonic form of myosin heavy chain.  |  Whalen, RG., et al. 1979. Proc Natl Acad Sci U S A. 76: 5197-201. PMID: 291935
    3. Myosin structure and function in cell motility.  |  Warrick, HM. and Spudich, JA. 1987. Annu Rev Cell Biol. 3: 379-421. PMID: 3318880
    4. The myosin alkali light chain proteins and their genes.  |  Barton, PJ. and Buckingham, ME. 1985. Biochem J. 231: 249-61. PMID: 3904738
    5. ATPase activity of myosin correlated with speed of muscle shortening.  |  Bárány, M. 1967. J Gen Physiol. 50: Suppl:197-218. PMID: 4227924
    6. Myosin types in human skeletal muscle fibers.  |  Billeter, R., et al. 1980. Histochemistry. 65: 249-59. PMID: 6445347

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Myosin Antibody (414)

    sc-52348
    500 µl supernatant
    $316.00