Date published: 2026-5-30

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MYL5 Antibody (SB-19): sc-100952

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Datasheets
  • MYL5 Antibody (SB-19) is a mouse monoclonal IgG1 κ MYL5 antibody provided at 100 µg/ml
  • raised against recombinant MYL5 of human origin
  • recommended for detection of MYL5 of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for MYL5 Antibody (SB-19). This work is in progress.
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    MYL5 Antibody (SB-19) is a mouse monoclonal IgG1 kappa light chain antibody that detects MYL5 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-MYL5 antibody (SB-19) is available as a non-conjugated format, providing researchers with a reliable tool for studying this important protein. Myosin regulatory light chain 5, also known as Myosin LC2, is encoded by the MYL5 gene and plays a crucial role in muscle contraction and various cellular movements, including cytokinesis and phagocytosis. MYL5 is primarily located in the cytoplasm of muscle cells and neurons, where MYL5 interacts with myosin heavy chains to form a functional myosin complex. Proper localization of MYL5 is essential for effective muscle contraction and cellular motility, as MYL5 ensures that myosin motor proteins can efficiently generate force by interacting with actin filaments. MYL5 is expressed in fetal muscle and adult tissues such as the retina, cerebellum, and basal ganglia, highlighting MYL5′s significance in both developmental and adult physiology. Understanding MYL5 dynamics and interactions within the cellular environment can provide valuable insights into muscle-related diseases and neurological disorders.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    MYL5 Antibody (SB-19) References:

    1. [Changes in composition of cardiac myosin light chains in dilated cardiomyopathy: effect on functional properties].  |  Khalina, IaN., et al. 2002. Biofizika. 47: 361-6. PMID: 11969177
    2. The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates.  |  Collins, C., et al. 1992. Hum Mol Genet. 1: 727-33. PMID: 1284596
    3. Effects of removal of light chain 2 on the ATPase activities of cardiac myosin from normal and thyrotoxic rabbits.  |  Kuo, TH. and Banerjee, SK. 1982. Biochim Biophys Acta. 707: 199-205. PMID: 6128032
    4. Human cardiac myosin light chains: sequence comparisons between myosin LC1 and LC2 from normal and idiopathic dilated cardiomyopathic hearts.  |  Holt, JC., et al. 1995. Mol Cell Biochem. 145: 89-96. PMID: 7659082
    5. Significance of the N-terminal fragment of myosin regulatory light chain for myosin-actin interaction.  |  Stepkowski, D., et al. 1995. Biochem Mol Biol Int. 35: 677-84. PMID: 7773203
    6. The proteolytic susceptibility of specific sites in myosin light chains is modulated by the filament conformation.  |  Roulet, A., et al. 1993. Eur J Biochem. 216: 89-101. PMID: 8365420
    7. Skeletal muscle myosin light chains are essential for physiological speeds of shortening.  |  Lowey, S., et al. 1993. Nature. 365: 454-6. PMID: 8413589

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    MYL5 Antibody (SB-19)

    sc-100952
    100 µg/ml
    $322.00