Molecular structure of Myeloperoxidase Inhibitor-I, CAS Number: 5351-17-7
Myeloperoxidase Inhibitor-I (CAS 5351-17-7)
See product citations (10)
Alternate Names:
4-Aminobenzoic hydrazide
Application:
Myeloperoxidase Inhibitor-I is an irreversible and specific inhibitor of the peroxidation activity of MPO
CAS Number:
5351-17-7
Purity:
>98%
Molecular Weight:
151.17
Molecular Formula:
C7H9N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Myeloperoxidase Inhibitor-I is a benzoic acid hydrazide analog acting as an irreversible and specific inhibitor of the peroxidation activity of MPO. Myeloperoxidase Inhibitor-I shows no effect in inhibition of catalase or glutathione peroxidase activities. Shows no effect on the production of superoxide by neutrophils. Shown to inhibit H2O2-induced apoptosis in HL-60.
Myeloperoxidase Inhibitor-I (CAS 5351-17-7) References
- Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species. | Fries, DM., et al. 2003. J Biol Chem. 278: 22901-7. PMID: 12690103
- Myeloperoxidase Inhibition Decreases the Expression of Collagen and Metallopeptidase in Mare Endometria under In Vitro Conditions. | Amaral, A., et al. 2021. Animals (Basel). 11: PMID: 33467081
- Impaired formation of neutrophil extracellular traps in patients with MDS. | Brings, C., et al. 2022. Blood Adv. 6: 129-137. PMID: 34653237
- Progress and Challenges in Quantifying Carbonyl-Metabolomic Phenomes with LC-MS/MS. | Sun, Y., et al. 2021. Molecules. 26: PMID: 34684729
- Blockade of CC Chemokine Receptor Type 3 Diminishes Pain and Enhances Opioid Analgesic Potency in a Model of Neuropathic Pain. | Pawlik, K., et al. 2021. Front Immunol. 12: 781310. PMID: 34795678
- Identification of rearing temperature-dependent host defense signaling against viral hemorrhagic septicemia virus infection. | Cho, SY., et al. 2022. Fish Shellfish Immunol. 123: 257-264. PMID: 35301114
- Green solvent free epoxidation of olefins by a heterogenised hydrazone-dioxidotungsten(vi) coordination compound. | Heydari, N., et al. 2022. RSC Adv. 12: 4813-4827. PMID: 35425511
- Monitoring Farmed Fish Welfare by Measurement of Cortisol as a Stress Marker in Fish Feces by Liquid Chromatography Coupled with Tandem Mass Spectrometry. | Meling, VA., et al. 2022. Molecules. 27: PMID: 35458678
- Opportunities for Molecular Imaging in Multiple Sclerosis Management: Linking Probe to Treatment. | Thomas, AM., et al. 2022. Radiology. 303: 486-497. PMID: 35471110
- Fluorescent probes for monitoring myeloperoxidase-derived hypochlorous acid: a comparative study. | Pierzchała, K., et al. 2022. Sci Rep. 12: 9314. PMID: 35660769
- Contact-dependent, polarized acidification response during neutrophil-epithelial interactions. | Cartwright, IM., et al. 2022. J Leukoc Biol. 112: 1543-1553. PMID: 35674095
- Inhibition of myeloperoxidase enhances immune checkpoint therapy for melanoma. | Liu, TW., et al. 2023. J Immunother Cancer. 11: PMID: 36805920
- Promising anticancer agents based on 8-hydroxyquinoline hydrazone copper(II) complexes. | Ribeiro, N., et al. 2023. Front Chem. 11: 1106349. PMID: 37025548
Inhibitor of:
Apoptosis, Enzyme, and MPO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myeloperoxidase Inhibitor-I, 1 g | sc-204107 | 1 g | $92.00 |