Mycobacterium tuberculosis RV3134 Dormancy Regulon Antibody (D5) is a mouse monoclonal IgG1 antibody that detects RV3134 protein in Mycobacterium tuberculosis through western blotting (WB). Mycobacterium tuberculosis, the leading cause of tuberculosis, is a Gram-positive obligate anaerobe that can remain dormant within the human host for extended periods, evading the immune response and complicating treatment efforts. RV3134 is a crucial component of the M. tuberculosis dormancy regulon, playing a significant role in the bacterium′s ability to adapt to hostile environmental conditions, such as low oxygen levels. RV3134 expression is upregulated in response to reduced oxygen tensions, which is vital for the pathogen′s survival during periods of dormancy. Understanding RV3134 function is essential, as this knowledge may provide insights into the mechanisms that allow M. tuberculosis to persist in the host and contribute to the development of new therapeutic strategies. Anti-RV3134 antibody (D5) serves as an invaluable tool for researchers studying the dormancy and pathogenicity of this critical human pathogen.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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