Molecular structure of MTSEA-Fluorescein, CAS Number: 1356019-48-1
MTSEA-Fluorescein (CAS 1356019-48-1)
See product citations (1)
Alternate Names:
(R)-2-Amino-2-[(5-fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate, Trifluoroacetic Acid Salt
Application:
MTSEA-Fluorescein is a thiol specific fluorescent probe
CAS Number:
1356019-48-1
Molecular Weight:
642.58
Molecular Formula:
C26H21F3N2O10S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
MTSEA-Fluorescein is a thiol specific fluorescent probe useful for protein topology and ion channel research. MTS-fluorophores may be useful in the real-time monitoring of conformational changes. MTS compounds have been shown to irreversibly activate the BNC1-G430C neuronal cation channel only when the channel was activated by protons. This suggests that fluorescent MTS reagents may be used as reporters of cell surface localization as well as the functional status of ion channels.
MTSEA-Fluorescein (CAS 1356019-48-1) References
- Direct physical measure of conformational rearrangement underlying potassium channel gating. | Mannuzzu, LM., et al. 1996. Science. 271: 213-6. PMID: 8539623
- Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome. | Goulet, CC., et al. 1998. J Biol Chem. 273: 30012-7. PMID: 9792722
- Protons activate brain Na+ channel 1 by inducing a conformational change that exposes a residue associated with neurodegeneration. | Adams, CM., et al. 1998. J Biol Chem. 273: 30204-7. PMID: 9804777
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MTSEA-Fluorescein, 5 mg | sc-218892 | 5 mg | $374.00 |