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MSK2 Antibody (2934C1a) is a mouse monoclonal IgG1 antibody that detects MSK2 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. MSK2, also known as RPS6KA4 or RSKB, is a crucial serine/threonine protein kinase composed of 772 amino acids, primarily localized in the nucleus. MSK2 plays a significant role in cellular signaling pathways, particularly in the regulation of growth-factor and stress-induced transcriptional activation. By utilizing magnesium as a cofactor, MSK2 catalyzes the ATP-dependent phosphorylation of target proteins, thereby influencing various cellular functions such as cell division, homeostasis, and apoptosis. MSK2′s nuclear localization enables direct interaction with transcription factors and other regulatory proteins, facilitating precise modulation of gene expression in response to external stimuli. Additionally, MSK2 is subject to alternative splicing, resulting in multiple isoforms that may have distinct regulatory roles, further underscoring the complexity of MSK2′s function in cellular signaling networks. Anti-MSK2 antibody (2934C1a) is an invaluable tool for researchers investigating the intricate mechanisms of cellular regulation and signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MSK2 Antibody (2934C1a) | sc-130653 | 100 µg/ml | $339.00 |