Date published: 2025-12-3

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Moperone (CAS 1050-79-9)

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Application:
Moperone is an aromatic compound used for biological research purposes
CAS Number:
1050-79-9
Purity:
98%
Molecular Weight:
355.45
Molecular Formula:
C22H26FNO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Moperone is an aromatic compound used for biological research purposes. Derived from the natural product moprolol, it shares structural similarities with the neurotransmitter serotonin. It has exhibited anxiolytic and antidepressant properties, as well as the capacity to modulate dopamine and norepinephrine release.


Moperone (CAS 1050-79-9) References

  1. High-performance liquid chromatographic determination of fluvoxamine and fluvoxamino acid in human plasma.  |  Ohkubo, T., et al. 2003. Anal Sci. 19: 859-64. PMID: 12834224
  2. Improvement of ocular blood flow with dopamine antagonists on ocular-hypertensive rabbit eyes.  |  Chiou, GC. and Chen, YJ. 1992. Zhongguo Yao Li Xue Bao. 13: 481-4. PMID: 1302433
  3. Measurement of haloperidol in human breast milk by high-performance liquid chromatography.  |  Ohkubo, T., et al. 1992. J Pharm Sci. 81: 947-9. PMID: 1432646
  4. Automated on-line in-tube solid-phase microextraction coupled with HPLC/MS/MS for the determination of butyrophenone derivatives in human plasma.  |  Kumazawa, T., et al. 2009. Anal Bioanal Chem. 394: 1161-70. PMID: 19387622
  5. The clinical position of moperone among the butyrophenones.  |  Gross, H. and Kaltenbäck, E. 1969. Nord Psykiatr Tidsskr. 23: 4-9. PMID: 5354545
  6. On the distribution and metabolism of neuroleptic drugs. II. Pharmacokinetics of moperone.  |  Heykants, JJ., et al. 1970. Arzneimittelforschung. 20: 1238-42. PMID: 5536800
  7. The distribution of the butyrophenones haloperidol, trifluperidol, moperone, and clofluperol in rats, and its relationship with their neuroleptic activity.  |  Janssen, PA. and Allewijn, FT. 1969. Arzneimittelforschung. 19: 199-208. PMID: 5818759
  8. A gas chromatographic method for the determination of fluanisone, moperone, aceperone and pipamperone in human plasma.  |  Quaglio, MP. and Bellini, AM. 1981. Farmaco Prat. 36: 204-14. PMID: 6112157
  9. Treatment of ocular hypertension and glaucoma with dopamine antagonists.  |  Chiou, GC. 1984. Ophthalmic Res. 16: 129-34. PMID: 6147806
  10. Determination of some butyrophenones in body fluids by gas chromatography with surface ionization detection.  |  Seno, H., et al. 1993. Nihon Hoigaku Zasshi. 47: 367-71. PMID: 8258900
  11. Analysis of the mechanism of the protective activity of some sympathomimetic amines in experimental ulcers.  |  Sandor, V. and Cuparencu, B. 1977. Pharmacology. 15: 208-17. PMID: 866398
  12. Effects of dopamine antagonists and agonist on cultured human Tenon's fibroblast cells.  |  Wu, KY., et al. 1996. Kaohsiung J Med Sci. 12: 388-93. PMID: 8753140
  13. Inhibitory effect of drugs with a ketone group on reduction of acetohexamide catalyzed by carbonyl reductase from rabbit kidney.  |  Imamura, Y., et al. 1997. J Enzyme Inhib. 11: 285-92. PMID: 9208371

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Moperone, 10 mg

sc-211927
10 mg
$300.00