Molecular structure of MNI-caged-L-glutamate, CAS Number: 295325-62-1
MNI-caged-L-glutamate (CAS 295325-62-1)
Alternate Names:
4-Methoxy-7-nitroindolinyl-caged-L-glutamate
Application:
MNI-caged-L-glutamate is rapidly and efficiently releases glutamate when photolysed with 300 - 380 nm light.
CAS Number:
295325-62-1
Purity:
≥97%
Molecular Weight:
323.3
Molecular Formula:
C14H17N3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MNI-caged-L-glutamate is a photoactivatable compound used extensively in neuroscience and cell biology research for the precise spatial and temporal control of glutamate receptor activation. The MNI (4-methoxy-7-nitroindolinyl) moiety serves as this photolabile cage, making the glutamate molecule inactive until it is exposed to light of a specific wavelength. MNI-caged-L-glutamate rapidly and efficiently releases glutamate when photolysed with light of wavelength between 300 - 380 nm. This compound is water-soluble, highly resistant to hydrolysis, and stable at neutral pH.
MNI-caged-L-glutamate (CAS 295325-62-1) References
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- Development of 4-methoxy-7-nitroindolinyl (MNI)-caged auxins which are extremely stable in planta. | Hayashi, K., et al. 2015. Bioorg Med Chem Lett. 25: 4464-71. PMID: 26364943
- A Postsynaptic Role for Short-Term Neuronal Facilitation in Dendritic Spines. | Yang, S., et al. 2016. Front Cell Neurosci. 10: 224. PMID: 27746721
- Photolysis of a Caged, Fast-Equilibrating Glutamate Receptor Antagonist, MNI-Caged γ-D-Glutamyl-Glycine, to Investigate Transmitter Dynamics and Receptor Properties at Glutamatergic Synapses. | Palma-Cerda, F., et al. 2018. Front Cell Neurosci. 12: 465. PMID: 30618624
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MNI-caged-L-glutamate, 10 mg | sc-361257 | 10 mg | $235.00 | |||
MNI-caged-L-glutamate, 50 mg | sc-361257A | 50 mg | $860.00 |