Molecular structure of MMP-2 Inhibitor II, CAS Number: 869577-51-5
MMP-2 Inhibitor II (CAS 869577-51-5)
Alternate Names:
(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane
Application:
MMP-2 Inhibitor II is an irreversible inhibitor of MMP-2 through active-site binding
CAS Number:
869577-51-5
Purity:
≥98%
Molecular Weight:
383.4
Molecular Formula:
C16H17NO6S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MMP-2 Inhibitor II is an oxirane analog of SB-3CT, pMS that is reported to be an irreversible inhibitor of MMP-2 through active-site binding. Although reported to be less potent, it has also been shown enhanced selectivity towards MMP-2 than SB-3CT, pMS. MMP-2 Inhibitor II is an inhibitor of MMP-1.
MMP-2 Inhibitor II (CAS 869577-51-5) References
- Potent mechanism-based inhibitors for matrix metalloproteinases. | Ikejiri, M., et al. 2005. J Biol Chem. 280: 33992-4002. PMID: 16046398
- Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation. | Xue, M., et al. 2014. Rheumatology (Oxford). 53: 2270-9. PMID: 24982240
Inhibitor of:
ADAMTS-17, MMP-1, MMP-2, and Protease.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MMP-2 Inhibitor II, 5 mg | sc-354092 | 5 mg | $240.00 |