Microtubule Marker Antibody (B364): sc-58800

Microtubule Marker Antibody (B364) is a mouse monoclonal IgM antibody that detects microtubules in human samples through immunofluorescence (IF) and immunohistochemistry with paraffin-embedded sections (IHCP). Microtubules play a crucial role in maintaining cell shape and facilitating intracellular transport, as integral components of the cytoskeleton. These dynamic structures, with diameters of approximately 24 nm and lengths that can extend from several micrometers to millimeters, are primarily composed of tubulin dimers that polymerize to form long, hollow tubes. The ability of microtubules to rapidly grow and shrink is essential for their function in processes such as mitosis, where microtubules form the mitotic spindle that segregates chromosomes during cell division. Additionally, microtubules are vital for the formation of cilia and flagella, which are necessary for cellular motility and fluid movement across cell surfaces. The interaction of microtubules with motor proteins, such as kinesins and dyneins, enables the transport of cellular cargo, highlighting their importance in cellular organization and function. Anti-microtubule antibody (B364) serves as a valuable tool for researchers studying the dynamics and behavior of microtubules, as well as their role in various cellular processes and diseases.

The preferred Microtubule Marker antibody is Microtubule Marker Antibody (AE-8): sc-73551.