Molecular structure of Metronidazole-OH, CAS Number: 4812-40-2
Metronidazole-OH (CAS 4812-40-2)
Alternate Names:
Hydroxymetronidazole
Application:
Metronidazole-OH is A chemical reagent used antibacterial and antiprotozoal research.
CAS Number:
4812-40-2
Molecular Weight:
187.15
Molecular Formula:
C6H9N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Metronidazole-OH is a chemical reagent used antibacterial and antiprotozoal research. Metronidazole-OH is a small molecule that exerts its effects by selectively binding to specific target molecules. It is thought to achieve this through the formation of a hydrogen bond between its hydroxylamine group and the target molecule. This interaction enables Metronidazole-OH to engage with a diverse range of molecules, including proteins, DNA, and other biomolecules. By forming these hydrogen bonds, Metronidazole-OH can influence the structure and function of the target molecule, leading to various biological effects. The precise consequences of this interaction may vary depending on the specific target molecule involved. It can result in modulation of enzymatic activity, alteration of protein conformation, interference with DNA replication or transcription, or other regulatory effects within cellular pathways.
Metronidazole-OH (CAS 4812-40-2) References
- Validated method for determination of eight banned nitroimidazole residues in natural casings by LC/MS/MS with solid-phase extraction. | Sun, H., et al. 2009. J AOAC Int. 92: 612-21. PMID: 19485222
- Determination and confirmation of metronidazole, dimetridazole, ronidazole and their metabolites in bovine muscle by LC-MS/MS. | Granja, RH., et al. 2013. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 30: 970-6. PMID: 23701281
- Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry. | Gadaj, A., et al. 2014. J Chromatogr B Analyt Technol Biomed Life Sci. 960: 105-15. PMID: 24793083
- Determination of the persistence of dimetridazole, metronidazole and ronidazole residues in black tiger shrimp (Penaeus monodon) tissue and their stability during cooking. | Gadaj, A., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 180-93. PMID: 25372355
- Sample preservation for the analysis of antibiotics in water. | Llorca, M., et al. 2014. J Chromatogr A. 1369: 43-51. PMID: 25441070
- Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry. | Meng, XS., et al. 2014. J AOAC Int. 97: 1538-45. PMID: 25632431
- Dynamics of active pharmaceutical ingredients loads in a Swiss university hospital wastewaters and prediction of the related environmental risk for the aquatic ecosystems. | Daouk, S., et al. 2016. Sci Total Environ. 547: 244-253. PMID: 26789362
- Multi-residue method for the determination of antibiotics and some of their metabolites in seafood. | Serra-Compte, A., et al. 2017. Food Chem Toxicol. 104: 3-13. PMID: 27908699
- Contribution of bacteriophage and plasmid DNA to the mobilization of antibiotic resistance genes in a river receiving treated wastewater discharges. | Lekunberri, I., et al. 2017. Sci Total Environ. 601-602: 206-209. PMID: 28551539
- Wastewater pollution differently affects the antibiotic resistance gene pool and biofilm bacterial communities across streambed compartments. | Subirats, J., et al. 2017. Mol Ecol. 26: 5567-5581. PMID: 28792642
- Microbial Flora Associated with the Halophyte-Salsola imbricate and Its Biotechnical Potential. | Bibi, F., et al. 2018. Front Microbiol. 9: 65. PMID: 29445362
- Practical approach to develop a multi-group screening method for detection of mycotoxins, pesticides and veterinary drugs in food. | Moretti, S., et al. 2020. J Mass Spectrom. 55: e4618. PMID: 32757493
- Assessing the diversity of bacterial communities from marine sponges and their bioactive compounds. | Bibi, F., et al. 2021. Saudi J Biol Sci. 28: 2747-2754. PMID: 34025160
- Antibiotics in Wastewater: Baseline of the Influent and Effluent Streams in Kuwait. | Gevao, B., et al. 2022. Toxics. 10: PMID: 35448435
- Pharmacokinetics of metronidazole and its major metabolite after a high intravenous dose. | Bergan, T., et al. 1984. Scand J Gastroenterol Suppl. 91: 113-23. PMID: 6588488
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Metronidazole-OH, 10 mg | sc-250408 | 10 mg | $174.00 | |||
Metronidazole-OH, 25 mg | sc-250408A | 25 mg | $500.00 |