Date published: 2025-9-5

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Methyl-1-thio-b-D-galactopyranoside (CAS 155-30-6)

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Alternate Names:
2-Hydroxymethyl-6-methylsulfanyl-tetrahydro-pyran-3,4,5-triol; Methyl-1-thio-b-D-galactoside
Application:
Methyl-1-thio-b-D-galactopyranoside is used to study the lac repressor system in bacteria
CAS Number:
155-30-6
Molecular Weight:
210.25
Molecular Formula:
C7H14O5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Methyl-1-thio-b-D-galactopyranoside, a derivative of galactose, has garnered significant attention in scientific research due to its utility as a substrate analog for studying enzyme kinetics and carbohydrate metabolism. This chemical serves as an important tool in enzymology, particularly in the investigation of glycosidases and glycosyltransferases. By mimicking the structure of natural substrates, methyl-1-thio-b-D-galactopyranoside allows researchers to explore the catalytic mechanisms of various glycosidic enzymes involved in carbohydrate processing. Furthermore, it facilitates the elucidation of substrate specificity and enzyme-substrate interactions, aiding in the development of novel inhibitors and modulators targeting carbohydrate-processing enzymes. In addition to its role in enzymatic studies, methyl-1-thio-b-D-galactopyranoside finds applications in bacterial genetics and microbiology. It serves as a substrate for bacterial galactosidases, enabling the identification and characterization of galactose-utilizing bacterial strains. Moreover, this compound has been utilized in bacterial growth assays and microbial fermentation studies aimed at understanding bacterial carbohydrate metabolism and its implications in microbial physiology and ecology. Overall, methyl-1-thio-b-D-galactopyranoside serves as a versatile tool in biochemical and microbiological research, offering valuable insights into the complex mechanisms governing carbohydrate metabolism and bacterial physiology.


Methyl-1-thio-b-D-galactopyranoside (CAS 155-30-6) References

  1. Interaction of effecting ligands with lac repressor and repressor-operator complex.  |  Barkley, MD., et al. 1975. Biochemistry. 14: 1700-12. PMID: 235964
  2. Replacement of alanine 58 by asparagine enables the melibiose carrier of Klebsiella pneumoniae to couple sugar transport to Na+.  |  Hama, H. and Wilson, TH. 1994. J Biol Chem. 269: 1063-7. PMID: 8288562
  3. Mutagenesis of acidic residues in putative membrane-spanning segments of the melibiose permease of Escherichia coli. I. Effect on Na(+)-dependent transport and binding properties.  |  Pourcher, T., et al. 1993. J Biol Chem. 268: 3209-15. PMID: 8428997

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Methyl-1-thio-b-D-galactopyranoside, 500 mg

sc-207879
500 mg
$150.00

Methyl-1-thio-b-D-galactopyranoside, 1 g

sc-207879A
1 g
$206.00