MES, Sodium Salt CAS: 71119-23-8
MF: C6H12NO4S•Na
MW: 217.22
A buffering agent used in biological and biochemical research including plant cell culture.

MES, Sodium Salt (CAS 71119-23-8)

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Alternate Names: sodium 2-(4-morpholinyl)ethanesulfonate; Sodium 2-Morpholinoethanesulfonate
Application: MES, Sodium Salt is a buffering agent used in biological and biochemical research including plant cell culture
CAS Number: 71119-23-8
Purity: ≥99%
Molecular Weight: 217.22
Molecular Formula: C6H12NO4S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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MES, Sodium Salt (2-(N-Morpholino)ethanesulfonic acid sodium salt) is a zwitterionic N-substituted aminosulfonic acid known as a Good's buffer, active in the pH range 6-8 with a pKa of 6.10 at 25° C. With a pKa value near physiological pH, it is not absorbed through cell membranes, and it is essentially transparent to UV light. MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. MES solutions can be prepared to the desired pH by titrating the free acid with sodium hydroxide.

Also available: MES hydrate (sc-216094); MES hemisodium salt (sc-216093); MES solution (sc-300959).


References

1. Good, N.E., et al. 1966. Biochemistry. 5: 467-477. PMID: 5942950
2. Graf, H., et al. 1994. Bioseparation. 4: 7-20. PMID: 7764588
3. Anfossi, L., et al. 2003. Ann Chim. 93: 499-512. PMID: 12911143
4. Mönch, S., et al. 2010. Anal. Biochem. 398: 150-160. PMID: 19903444
5. Teste, B., et al. 2010. Talanta. 81: 1703-1710. PMID: 20441961

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in water (0.5 g/l).
Storage :
Store at 4° C
pK Values :
pKa: 6.1
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
PubChem CID :
MDL Number :
MFCD00065473
EC Number :
275-203-2
Beilstein Registry :
3765682
SMILES :
C1COCCN1CCS(=O)(=O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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