Molecular structure of MDL 105,212 hydrochloride, CAS Number: 167261-59-8
MDL 105,212 hydrochloride (CAS 167261-59-8)
Alternate Names:
1-[2-[(3R)-3-(3,4-dichlorophenyl)-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]ethyl]-4-phenylpiperidine-4-carboxamide hydrochloride
Application:
MDL 105,212 hydrochloride is a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors.
CAS Number:
167261-59-8
Molecular Weight:
677.06
Molecular Formula:
C34H39Cl2N3O5•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
MDL 105,212 hydrochloride is a non-peptide tachykinin antagonist that has high affinity for NK1 and NK2 receptors.
MDL 105,212 hydrochloride (CAS 167261-59-8) References
Identification and chemical synthesis of MDL 105,212, a non-peptide tachykinin antagonist with high affinity for NK1 and NK2 receptors: T.P. Burkholder, et al.; Bioorg. Med. Chem. Lett. 6, 951 (1996) In vitro and in vivo characterization of MDL 105,212A, a nonpeptide NK-1/NK-2 tachykinin receptor antagonist: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 277, 840 (1996) Effect of MDL 105,212, a nonpeptide NK-1/NK-2 receptor antagonist in an allergic guinea pig model: E.M. Kudlacz, et al.; J. Pharmacol. Exp. Ther. 279, 732 (1996)Inhibitor of:
Tachykinin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MDL 105,212 hydrochloride, 1 mg | sc-221877 | 1 mg | $92.00 | |||
MDL 105,212 hydrochloride, 5 mg | sc-221877A | 5 mg | $292.00 |