Date published: 2026-5-9

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MCOPPB trihydrochloride (CAS 1028969-49-4 (free base))

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Application:
MCOPPB trihydrochloride is a high affinity NOP receptor (KOR-3) agonist
CAS Number:
1028969-49-4 (free base)
Molecular Weight:
518.01
Molecular Formula:
C26H40N43HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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MCOPPB trihydrochloride is a high affinity NOP receptor (KOR-3) agonist. MCOPPB trihydrochloride is extensively utilized in neurochemical research, particularly for its role in studying neurotransmitter systems. This compound is valuable in exploring the mechanisms of receptor binding and activation, providing insights into the modulation of neurotransmitter release. Researchers employ MCOPPB trihydrochloride in various assays to understand better the dynamics of receptor-ligand interactions, which can influence the development of more efficient receptor-based models. Its high specificity and affinity for certain receptor types make it an important tool in the characterization of receptor subtypes, aiding in the mapping of neural pathways.


MCOPPB trihydrochloride (CAS 1028969-49-4 (free base)) References

  1. Deciphering intracellular localization and physiological role of nociceptin and nocistatin.  |  Tariq, S., et al. 2013. Peptides. 43: 174-83. PMID: 23454174
  2. Quantitative Signaling and Structure-Activity Analyses Demonstrate Functional Selectivity at the Nociceptin/Orphanin FQ Opioid Receptor.  |  Chang, SD., et al. 2015. Mol Pharmacol. 88: 502-11. PMID: 26134494
  3. CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor.  |  Takenaga, T., et al. 2021. Viruses. 13: PMID: 34578344
  4. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects.  |  Raffaele, M., et al. 2022. Geroscience. 44: 463-483. PMID: 34820764
  5. Abrogation of Cellular Senescence Induced by Temozolomide in Glioblastoma Cells: Search for Senolytics.  |  Beltzig, L., et al. 2022. Cells. 11: PMID: 36010664

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

MCOPPB trihydrochloride, 5 mg

sc-361249
5 mg
$96.00

MCOPPB trihydrochloride, 25 mg

sc-361249A
25 mg
$386.00