

MATP Antibody (7K-2) is a mouse monoclonal IgG2b light chain antibody that detects membrane-associated transporter protein (MATP) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). MATP is a crucial melanocyte differentiation antigen composed of 530 amino acids, characterized by its ability to span the lipid bilayer 12 times, which is essential for function as a transporter. MATP is predominantly expressed in melanoma cell lines, highlighting potential role in skin cancer, as MATP is not significantly present in normal tissues. MATP expression is transcriptionally regulated by MITF, a melanocyte-specific transcription factor that can influence activity either directly or through remote regulatory sequences. Notably, mutations in the MATP gene have been associated with albinism, underscoring MATP importance in pigmentation processes. Anti-MATP antibody (7K-2) is an invaluable tool for researchers investigating molecular mechanisms underlying melanoma and other related conditions, providing insights into MATP role in both health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
MATP Antibody (7K-2) | sc-100780 | 50 µg/0.5 ml | $322.00 |