Makorin-2 Antibody (FG-9): sc-101118
- Makorin-2 Antibody (FG-9) is a mouse monoclonal IgG1 κ provided at 100 µg/ml
- raised against recombinant Makorin-2 of human origin
- recommended for detection of Makorin-2 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Makorin-2 Antibody (FG-9). This work is in progress.
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Makorin-2 Antibody (FG-9) is a mouse monoclonal IgG1 antibody that detects Makorin-2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Makorin-2, also known as RNF62, HSPC070, or MKRN2, is a highly conserved protein characterized by its unique structure, which includes four C3H-type zinc fingers and a RING-type zinc finger. This structural composition enables Makorin-2 to function as an E3 ubiquitin ligase, facilitating the ubiquitination process that tags proteins for degradation, thereby regulating various cellular processes. The role of Makorin-2 in modulating protein levels within cells is vital for maintaining cellular homeostasis and influencing pathways such as neurogenesis and tumor progression. Makorin-2 is overexpressed in several cancer cell lines, indicating potential involvement in oncogenic processes. Makorin-2 is co-expressed with Raf-1 in various tissues and cell lines, suggesting a collaborative role in signaling pathways that could impact cell growth and survival. Makorin-2 (FG-9) antibody serves as an essential tool for researchers investigating the multifaceted roles of this protein in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Makorin-2 Antibody (FG-9) | sc-101118 | 100 µg/ml | $339.00 |