LTβR Antibody (Ls-14) is a rat monoclonal IgG2a light chain antibody that detects LTβR in mouse samples through western blotting (WB) and flow cytometry (FCM) applications. LTβR, or lymphotoxin β receptor, plays a crucial role in the immune system by mediating the development and organization of lymphoid tissues, which are essential for effective immune responses. This receptor is primarily located on the surface of various cell types, excluding T and B lymphocytes, and is activated upon binding with the heterotrimeric lymphotoxin LT-α1/β2 complex. The activation of LTβR triggers downstream signaling pathways, including the NF-kB pathway, which is vital for regulating immune cell survival and apoptosis. Understanding the function and signaling mechanisms of LTβR is important for elucidating its role in immune system development and potential implications in autoimmune diseases and lymphoid malignancies. Anti-LTβR antibody (Ls-14) is an invaluable tool for researchers investigating the complexities of immune regulation and lymphoid organ development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LTβR Antibody (Ls-14) | sc-80167 | 100 µg/ml | $322.00 |