LTβR Antibody (5G11): sc-52696
- LTβR Antibody (5G11) is a rat monoclonal IgG2a provided at 100 µg/ml
- raised against the extracellular domain of LTβR of mouse origin
- recommended for detection of LTβR of mouse origin by FCM
- available conjugated to FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for LTβR Antibody (5G11). This work is in progress.
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SEE ALSO...
LTβR Antibody (5G11) is a rat monoclonal IgG2a antibody that detects LTβR in mouse samples through flow cytometry (FCM). LTβR, or lymphotoxin β receptor, plays a crucial role in the immune system by mediating the development and organization of lymphoid tissues, which are essential for effective immune responses. This receptor is primarily located on the surface of various cell types, excluding T and B lymphocytes, and is activated upon binding with the heterotrimeric lymphotoxin LT-α1/β2. LTβR activation triggers downstream signaling pathways, including the NFκB pathway, which is vital for regulating immune responses and promoting apoptosis in certain contexts. The importance of LTβR in lymphoid organ development highlights its potential as a therapeutic target in diseases characterized by immune dysregulation, such as autoimmune disorders and certain cancers. Anti-LTβR antibody (5G11) is an invaluable tool for researchers investigating the complexities of immune system function and the role of lymphoid structures in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LTβR Antibody (5G11) | sc-52696 | 100 µg/ml | $316.00 | |||
LTβR Antibody (5G11) FITC | sc-52696 FITC | 200 µg/ml |