Molecular structure of Lithium acetate, CAS Number: 546-89-4
Lithium acetate (CAS 546-89-4)
Alternate Names:
Acetic acid lithium salt
Application:
Lithium acetate is a metal acetate for proteomics research
CAS Number:
546-89-4
Molecular Weight:
65.99
Molecular Formula:
C2H3O2•Li
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Lithium acetate is a chemical compound with the formula LiCH3COO, comprising a lithium ion (Li⁺) and an acetate ion (CH3COO⁻). This compound is known for its role in various chemical and biological research applications, particularly due to its unique properties as a lithium salt of acetic acid. In the realm of molecular biology, lithium acetate is extensively used as a facilitator of DNA transformation into yeast cells. The mechanism underlying this process involves the destabilization of the cell membrane by lithium ions, which enhances the uptake of foreign DNA into the cell. This property makes lithium acetate an invaluable tool in genetic engineering and molecular biology research for the introduction of plasmids into yeast, enabling the study of gene expression, protein function, and the genetic manipulation of these organisms.
Lithium acetate (CAS 546-89-4) References
- High efficiency transformation by electroporation of Pichia pastoris pretreated with lithium acetate and dithiothreitol. | Wu, S. and Letchworth, GJ. 2004. Biotechniques. 36: 152-4. PMID: 14740498
- A rapid and simple procedure for high-efficiency lithium acetate transformation of cryopreserved Schizosaccharomyces pombe cells. | Suga, M. and Hatakeyama, T. 2005. Yeast. 22: 799-804. PMID: 16088874
- High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. | Gietz, RD. and Schiestl, RH. 2007. Nat Protoc. 2: 31-4. PMID: 17401334
- Extraction of genomic DNA from yeasts for PCR-based applications. | Lõoke, M., et al. 2011. Biotechniques. 50: 325-8. PMID: 21548894
- Visualization of the synergistic effect of lithium acetate and single-stranded carrier DNA on Saccharomyces cerevisiae transformation. | Pham, TA., et al. 2011. Curr Genet. 57: 233-9. PMID: 21562715
- High efficiency electrotransformation of Lactobacillus casei. | Welker, DL., et al. 2015. FEMS Microbiol Lett. 362: 1-6. PMID: 25670703
- Transformation of Schizosaccharomyces pombe: Protoplast Procedure. | Murray, JM., et al. 2016. Cold Spring Harb Protoc. 2016: pdb.prot090977. PMID: 27037076
- Single-step Marker Switching in Schizosaccharomyces pombe Using a Lithium Acetate Transformation Protocol. | Brown, SD. and Lorenz, A. 2016. Bio Protoc. 6: PMID: 28352647
- Expression of Plant Receptor Kinases in Yeast. | Barberini, ML. and Muschietti, JP. 2017. Methods Mol Biol. 1621: 21-27. PMID: 28567639
- Transformation of Schizosaccharomyces japonicus. | Aoki, K. and Niki, H. 2017. Cold Spring Harb Protoc. 2017: pdb.prot091850. PMID: 28733403
- Targeted gene replacement at the URA3 locus of the basidiomycetous yeast Pseudozyma antarctica and its transformation using lithium acetate treatment. | Yarimizu, T., et al. 2017. Yeast. 34: 483-494. PMID: 28810289
- Application of combined acetate salt based multiple analyte adduct formation in signal separated quantification performed for the purposes of forensic toxicology with liquid chromatography-tandem mass spectrometry - Discussion on the basis of salicylic acid applied as a model drug. | Dziadosz, M. 2019. Forensic Sci Int. 297: 249-253. PMID: 30849692
- Niobium Tungsten Oxide in a Green Water-in-Salt Electrolyte Enables Ultra-Stable Aqueous Lithium-Ion Capacitors. | Dong, S., et al. 2020. Nanomicro Lett. 12: 168. PMID: 34138154
- A novel study on preparation of H2TiO3-lithium adsorbent with titanyl sulfate as titanium source by inorganic precipitation-peptization method. | Zhang, LY., et al. 2018. RSC Adv. 8: 1385-1391. PMID: 35540889
- Enhanced Electrochemical Performance of the LiNi0.5Mn1.5O4 Cathode Material by the Construction of Uniform Lithium Silicate Nanoshells. | Zhang, Y., et al. 2023. ACS Appl Mater Interfaces. 15: 1418-1431. PMID: 36563182
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lithium acetate, 100 g | sc-235503 | 100 g | $89.00 | |||
Lithium acetate, 1 kg | sc-235503A | 1 kg | $171.00 | |||
Lithium acetate, 2.5 kg | sc-235503B | 2.5 kg | $379.00 | |||
Lithium acetate, 5 kg | sc-235503C | 5 kg | $714.00 | |||
Lithium acetate, 10 kg | sc-235503D | 10 kg | $1358.00 |