Listeria monocytogenes Antibody (LZH1): sc-52059

Listeria monocytogenes Antibody (LZH1) is a mouse monoclonal IgG1 antibody that detects Listeria monocytogenes with specificity by western blotting (WB). Listeria monocytogenes is a significant food-borne pathogen known for invading and surviving within host cells, leading to severe health complications such as listeriosis, which can result in meningitis and septicemia, particularly in vulnerable populations like newborns, elderly, and immunocompromised individuals. The pathogenicity of Listeria monocytogenes (LZH1) monoclonal antibody targets a pathogen largely attributed to its unique ability to manipulate host cell machinery, particularly through internalins, which facilitate bacterial entry into host cells by binding to specific adhesion factors. Once inside, anti-Listeria monocytogenes antibody (LZH1) recognizes a pathogen that employs a remarkable strategy to escape host immune response by utilizing actin polymerization to propel itself within the cytoplasm, creating a comet-tail structure for rapid movement and cell-to-cell spread. This dynamic interaction underscores LZH1′s importance in studying infection mechanisms and highlights its critical role in understanding bacterial pathogenesis and developing potential therapeutic strategies.