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Linoelaidic Acid (CAS 506-21-8)

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Alternate Names:
9E,12E-octadecadienoic acid
Application:
Linoelaidic Acid is an all-trans fatty acid homolog of linoleic acid
CAS Number:
506-21-8
Purity:
≥98%
Molecular Weight:
280.5
Molecular Formula:
C18H32O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Linoelaidic acid is a trans fatty acid that functions as a substrate for enzymes involved in lipid metabolism. It is involved in the regulation of cellular processes related to lipid synthesis and storage. Linoelaidic acid can modulate the activity of key enzymes involved in lipid metabolism, affecting the production of various lipid species within cells. At the molecular level, linoelaidic acid can interact with specific enzymes and alter their activity, leading to changes in lipid composition and metabolism. This can have downstream effects on cellular functions and signaling pathways related to lipid homeostasis. Linoelaidic acid plays a role in influencing lipid metabolism and cellular processes related to lipid homeostasis at the molecular level.


Linoelaidic Acid (CAS 506-21-8) References

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  2. Inactivation of T5 phage by cis-vaccenic acid, an antivirus substance from Rhodopseudomonas capsulata, and by unsaturated fatty acids and related alcohols.  |  Hirotani, H., et al. 1991. FEMS Microbiol Lett. 61: 13-7. PMID: 2004693
  3. Trans fatty acids enhanced β-amyloid induced oxidative stress in nerve growth factor differentiated PC12 cells.  |  Tsai, SJ., et al. 2012. Neurochem Res. 37: 786-94. PMID: 22198657
  4. Optimization of extraction conditions and fatty acid characterization of Lactobacillus pentosus cell-bound biosurfactant/bioemulsifier.  |  Vecino, X., et al. 2015. J Sci Food Agric. 95: 313-20. PMID: 24798413
  5. The trans fatty acids content of selected foods in Malaysia.  |  Akmar, ZD., et al. 2013. Malays J Nutr. 19: 87-98. PMID: 24800387
  6. Linoelaidic acid enhances adipogenic differentiation in adipose tissue-derived stromal cells through suppression of Wnt/β-catenin signaling pathway in vitro.  |  Wang, J., et al. 2016. Prostaglandins Leukot Essent Fatty Acids. 110: 1-7. PMID: 27255637
  7. trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway.  |  Hirata, Y., et al. 2017. J Biol Chem. 292: 8174-8185. PMID: 28360100
  8. Anti-obesity potentiality of Tapra fish (Opisthopterus tardoore) oil.  |  Pradhan, S., et al. 2020. J Food Biochem. 44: e13448. PMID: 32881000
  9. Effect of konjac glucomannan on metabolites in the stomach, small intestine and large intestine of constipated mice and prediction of the KEGG pathway.  |  Zhang, Q., et al. 2021. Food Funct. 12: 3044-3056. PMID: 33710209
  10. Antioxidant action of yerba mate on carcass and meat characteristics and fatty acid profile in meat and fat of lambs finished in tropical pastures.  |  Baerley, VR., et al. 2023. Trop Anim Health Prod. 55: 109. PMID: 36917307
  11. Modulation of rabbit neutrophil aggregation and degranulation by free fatty acids.  |  Naccache, PH., et al. 1984. J Leukoc Biol. 36: 333-40. PMID: 6592282
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  13. Occurrence of 5c,8c,11c,15t-eicosatetraenoic acid and other unusual polyunsaturated fatty acids in rats fed partially hydrogenated canola oil.  |  Ratnayake, WM., et al. 1994. Lipids. 29: 707-14. PMID: 7861938
  14. Platelet trans fatty acids in relation to angiographically assessed coronary artery disease.  |  Hodgson, JM., et al. 1996. Atherosclerosis. 120: 147-54. PMID: 8645355

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Linoelaidic Acid, 100 mg

sc-205375
100 mg
$21.00

Linoelaidic Acid, 250 mg

sc-205375A
250 mg
$67.00