Molecular structure of Lignoceric Acid, CAS Number: 557-59-5
Lignoceric Acid (CAS 557-59-5)
Alternate Names:
FL 88
Application:
Lignoceric Acid is a 24-carbon saturated fatty acid created as a byproduct of lignan production
CAS Number:
557-59-5
Molecular Weight:
368.63
Molecular Formula:
C24H48O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lignoceric Acid is a saturated fatty acid characterized by a lengthy carbon backbone consisting of twenty-four carbons. It falls under the category of medium-chain fatty acids and occurs naturally in sources such as animal fat and certain types of algae. This compound holds significant importance as an intermediate in the synthesis of fatty acids, waxes, and other lipid molecules. Lignoceric Acid undergoes metabolism by the enzyme fatty acid synthase, resulting in the formation of fatty acyl-CoA molecules. These molecules are subsequently utilized in the synthesis of other fatty acids and lipids.
Lignoceric Acid (CAS 557-59-5) References
- Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy. | Singh, I., et al. 1992. J Biol Chem. 267: 13306-13. PMID: 1618832
- Persistence of essential fatty acid deficiency in cystic fibrosis despite nutritional therapy. | Aldámiz-Echevarría, L., et al. 2009. Pediatr Res. 66: 585-9. PMID: 19851226
- Exogenous [1-(14)C]lignoceric acid uptake by neurons, astrocytes and myelin, as compared to incorporation of [1-(14)C]palmitic and stearic acids. | Morand, O., et al. 1981. Neurochem Int. 3: 329-34. PMID: 20487830
- Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases. | Lazo, O., et al. 1990. J Lipid Res. 31: 583-95. PMID: 2141053
- Harvest Season Significantly Influences the Fatty Acid Composition of Bee Pollen. | Al-Kahtani, SN., et al. 2021. Biology (Basel). 10: PMID: 34199497
- Assessment of Plasma Phospholipid Very-Long-Chain Saturated Fatty Acid Levels and Healthy Aging. | Bockus, LB., et al. 2021. JAMA Netw Open. 4: e2120616. PMID: 34383061
- A comparative study of stearic and lignoceric acid oxidation by human skin fibroblasts. | Singh, H. and Poulos, A. 1986. Arch Biochem Biophys. 250: 171-9. PMID: 3767370
- Synthesis of cerebronic acid from lignoceric acid by rat brain preparation. Some properties and distribution of the -hydroxylation system. | Hoshi, M. and Kishimoto, Y. 1973. J Biol Chem. 248: 4123-30. PMID: 4145326
- Purification and characterization of the heat-stable factors essential for the conversion of lignoceric acid to cerebronic acid and glutamic acid: identification of N-acetyl-L-aspartic acid. | Shigematsu, H., et al. 1983. J Neurochem. 40: 814-20. PMID: 6131106
- Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. | Singh, I., et al. 1984. Proc Natl Acad Sci U S A. 81: 4203-7. PMID: 6588384
- Further characterization of the heat-stable factor in the alpha-hydroxylation and oxidation of lignoceric acid in brain: effect of acidic amino acids and hexose-phosphates on brain fatty acid metabolism. | Shimeno, H., et al. 1983. Arch Biochem Biophys. 223: 95-106. PMID: 6859867
- Lignoceric acid biosynthesis in the developing brain. Activities of mitochondrial acetyl-CoA-dependent synthesis and microsomal malonyl-CoA chain-elongating system in relation to myelination. Comparison between normal mouse and dysmyelinating mutants (quaking and jimpy). | Bourre, JM., et al. 1977. Eur J Biochem. 72: 41-7. PMID: 836393
- Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy. | Sandhir, R., et al. 1998. J Lipid Res. 39: 2161-71. PMID: 9799802
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Lignoceric Acid, 50 mg | sc-205373 | 50 mg | $27.00 | |||
Lignoceric Acid, 100 mg | sc-205373A | 100 mg | $32.00 | |||
Lignoceric Acid, 1 g | sc-205373B | 1 g | $311.00 |