Leukocyte marker antibody: sc-52695

Leukocyte Marker Antibody (50-4B1) is a mouse monoclonal IgG1 antibody that detects the Leukocyte Marker protein of mouse and rat origin by immunofluorescence (IF). Anti-Leukocyte Marker antibody (50-4B1) is available as a non-conjugated format. Leukocytes, or white blood cells, play a crucial role in the immune system, defending the body against infections and foreign substances. These cells are primarily produced in the bone marrow and are also abundant in the lymphatic system, spleen, and various tissues throughout the body. The structure of leukocytes is vital for their function; unique surface markers allow for the identification and classification of different leukocyte types, such as lymphocytes, monocytes, and granulocytes. Each type has a distinct role in immune response, with lymphocytes being key players in adaptive immunity, while granulocytes are essential for innate immunity. Accurate identification and study of these cells using Leukocyte Marker (50-4B1) antibody is important for understanding immune responses and developing therapies for various diseases, including autoimmune disorders and cancers.

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Leukocyte marker antibody References:

1. Leukocyte function-associated antigen-1: structure, function and application prospects.  |  Xingyuan, M., et al. 2006. Protein Pept Lett. 13: 397-400. PMID: 16712517
2. Human leukocyte antigen B58 supertype and human immunodeficiency virus type 1 infection in native Africans.  |  Lazaryan, A., et al. 2006. J Virol. 80: 6056-60. PMID: 16731944
3. Soluble human leukocyte antigen: a diagnostic indicator of rheumatoid arthritis?  |  Hayman, MW., et al. 2006. J Immunol Methods. 315: 19-26. PMID: 16893550
4. Pathophysiology of leukocyte-tissue interactions.  |  Molteni, R., et al. 2006. Curr Opin Cell Biol. 18: 491-8. PMID: 16904306
5. Human leukocyte antigen F protein is expressed in the extra-villous trophoblasts but not on the cell surface of them.  |  Nagamatsu, T., et al. 2006. Am J Reprod Immunol. 56: 172-7. PMID: 16911712
6. Polymorphonuclear leukocyte dysfunction syndrome in patients with increasing sepsis severity.  |  Kaufmann, I., et al. 2006. Shock. 26: 254-61. PMID: 16912650
7. Leukocyte-specific protein 1 (LSP1): a regulator of leukocyte emigration in inflammation.  |  Jongstra-Bilen, J. and Jongstra, J. 2006. Immunol Res. 35: 65-74. PMID: 17003510
8. Human leukocyte antigen class I and MICA haplotypes in a multicase family with Cladophialophora carrionii chromoblastomycosis.  |  Naranjo, F., et al. 2006. Tissue Antigens. 68: 287-92. PMID: 17026462
9. The new human leukocyte antigen-A*2631 is characterized by a new HLA-A polymorphism at amino acid position 62.  |  Balas, A., et al. 2006. Tissue Antigens. 68: 344-5. PMID: 17026472

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Leukocyte Marker Antibody (50-4B1) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-Leukocyte Marker Antibody (50-4B1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Leukocyte Marker Antibody (50-4B1) Specifications

Alternate Product Name: Leukocyte Marker

Product Clone Name: 50-4B1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Leukocyte marker

Epitope Species: rat

Product Reactivity/Detection: all leucocytes (anti-LCA like)

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Leukocyte Marker Antibody (50-4B1): N/A