Molecular structure of Leu-pNA, Chromogenic Substrate, CAS Number: 4178-93-2
Leu-pNA, Chromogenic Substrate (CAS 4178-93-2)
Application:
Leu-pNA, Chromogenic Substrate is an aminopeptidase substrate used to detect/evaluate functionality of aminopeptidases.
CAS Number:
4178-93-2
Purity:
≥98%
Molecular Weight:
251.3
Molecular Formula:
C12H17N3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Leu-pNA, Chromogenic Substrate is a substrate for aminopeptidase, a zinc dependent enzyme that assists in the digestion of proteins. The compound has been used in an ELISA assay to detect biological functionality of chicken aminopeptidase produced by E. coli. The compound has also been used to characterize the native IRAP (placental leucine aminopeptidase). Leu-pNA, Chromogenic Substrate is documented for use with pure samples as well as cell extracts in vitro. Leu-pNA, Chromogenic Substrate is a substrate of CD13.
Leu-pNA, Chromogenic Substrate (CAS 4178-93-2) References
- Aminopeptidase PC from the hepatopancreas of the Kamchatka crab Paralithodes camtshatica. | Rudenskaya, GN., et al. 2000. Biochemistry (Mosc). 65: 164-70. PMID: 10713541
- Purification and some properties of an aminopeptidase from the seeds of Cannabis sativa. | Arima, K., et al. 2000. Biosci Biotechnol Biochem. 64: 1055-7. PMID: 10879480
- Immunoaffinity purification and characterization of native placental leucine aminopeptidase/oxytocinase from human placenta. | Nakanishi, Y., et al. 2000. Placenta. 21: 628-34. PMID: 10985965
- Purification and characterization of an aminopeptidase from the edible basidiomycete Grifola frondosa. | Nishiwaki, T. and Hayashi, K. 2001. Biosci Biotechnol Biochem. 65: 424-7. PMID: 11302180
- A secreted aminopeptidase of Pseudomonas aeruginosa. Identification, primary structure, and relationship to other aminopeptidases. | Cahan, R., et al. 2001. J Biol Chem. 276: 43645-52. PMID: 11533066
- Thiolation of polycarbophil enhances its inhibition of intestinal brush border membrane bound aminopeptidase N. | Bernkop-Schnürch, A., et al. 2001. J Pharm Sci. 90: 1907-14. PMID: 11745748
- Development of buccal drug delivery systems based on a thiolated polymer. | Langoth, N., et al. 2003. Int J Pharm. 252: 141-8. PMID: 12550789
- Characterization of a novel rat thymocyte costimulating antigen by the monoclonal antibody 1.3. | Bristol, LA., et al. 1992. J Immunol. 148: 332-8. PMID: 1345919
- Metal ion modulation of cystinyl aminopeptidase. | Laeremans, H., et al. 2005. Biochem J. 390: 351-7. PMID: 15885030
- [Aminopeptidase activity in populations of human blood mononuclear cells]. | Kunz, D., et al. 1990. Allerg Immunol (Leipz). 36: 233-43. PMID: 1982982
- [Expression and biological function analysis of chicken aminopeptidase N]. | Yin, X., et al. 2010. Sheng Wu Gong Cheng Xue Bao. 26: 470-5. PMID: 20575434
- Purification and characterization of a novel fibrinolytic enzyme from culture supernatant of Pleurotus ostreatus. | Liu, XL., et al. 2014. J Microbiol Biotechnol. 24: 245-53. PMID: 24248089
- A thermo-stable lysine aminopeptidase from Pseudomonas aeruginosa: Isolation, purification, characterization, and sequence analysis. | Wu, YT., et al. 2014. J Basic Microbiol. 54: 1110-9. PMID: 24442752
- Separation of peptide transport and hydrolysis in trimethionine uptake by Saccharomyces cerevisiae. | Parker, DD., et al. 1980. J Bacteriol. 143: 1066-9. PMID: 7009548
- [Synthesis of three- and tetrapeptides catalyzed by subtilisin suspensions in organic solvents]. | Getun, IV., et al. 1998. Bioorg Khim. 24: 306-12. PMID: 9612574
Substrate of:
Aminopeptidase, CD13, Chromogenic, and IRAP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Leu-pNA, Chromogenic Substrate, 100 mg | sc-201164 | 100 mg | $96.00 |