Molecular structure of LDFT Glycan, CAS Number: 20768-11-0
LDFT Glycan (CAS 20768-11-0)
Alternate Names:
Lactodifucotetraose; Difucosyl lactose
CAS Number:
20768-11-0
Molecular Weight:
634.58
Molecular Formula:
C24H42O19
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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LDFT Glycan is a complex oligosaccharide naturally occurring in milk, exhibiting diverse biological activities, including prebiotic effects, anti-adhesive properties, and immune modulation. The synthesis of LDFT Glycan poses challenges due to its intricate structure, prompting researchers to explore efficient production methods. LDFT Glycan involves interactions with specific receptors on the surfaces of host cells and bacteria. Specifically, LDFT Glycan can bind to receptors on beneficial bacteria, promoting their growth and activity. Moreover, it can also bind to receptors on pathogenic bacteria, inhibiting their adhesion to host cells and suppressing their growth.
LDFT Glycan (CAS 20768-11-0) References
- The principal fucosylated oligosaccharides of human milk exhibit prebiotic properties on cultured infant microbiota. | Yu, ZT., et al. 2013. Glycobiology. 23: 169-77. PMID: 23028202
- Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes. | Yu, ZT., et al. 2013. Glycobiology. 23: 1281-92. PMID: 24013960
- Design of an α-L-transfucosidase for the synthesis of fucosylated HMOs. | Saumonneau, A., et al. 2016. Glycobiology. 26: 261-9. PMID: 26582607
- Lactodifucotetraose, a human milk oligosaccharide, attenuates platelet function and inflammatory cytokine release. | Newburg, DS., et al. 2016. J Thromb Thrombolysis. 42: 46-55. PMID: 26743063
- Neutral Human Milk Oligosaccharides Are Associated with Multiple Fixed and Modifiable Maternal and Infant Characteristics. | Wang, M., et al. 2020. Nutrients. 12: PMID: 32244912
- The Human Milk Oligosaccharides 3-FL, Lacto-N-Neotetraose, and LDFT Attenuate Tumor Necrosis Factor-α Induced Inflammation in Fetal Intestinal Epithelial Cells In Vitro through Shedding or Interacting with Tumor Necrosis Factor Receptor 1. | Cheng, L., et al. 2021. Mol Nutr Food Res. 65: e2000425. PMID: 33465830
- Microbial production of human milk oligosaccharide lactodifucotetraose. | Zhang, A., et al. 2021. Metab Eng. 66: 12-20. PMID: 33812022
- Correlations between oligosaccharides in breast milk and the composition of the gut microbiome in breastfed infants. | Shang, J., et al. 2022. J Dairy Sci. 105: 4818-4828. PMID: 35400500
- 1H NMR Metabolomics of Chinese Human Milk at Different Stages of Lactation among Secretors and Non-Secretors. | Kortesniemi, M., et al. 2022. Molecules. 27: PMID: 36080292
- Identification of a peptide which binds to the carbohydrate-specific monoclonal antibody B3. | Hoess, R., et al. 1993. Gene. 128: 43-9. PMID: 7685300
- Characterization of the binding specificity of Anguilla anguilla agglutinin (AAA) in comparison to Ulex europaeus agglutinin I (UEA-I). | Baldus, SE., et al. 1996. Glycoconj J. 13: 585-90. PMID: 8872115
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LDFT Glycan, 1 mg | sc-221839 | 1 mg | $520.00 | |||
LDFT Glycan, 2 mg | sc-221839A | 2 mg | $1040.00 |