Date published: 2026-4-24

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Larixyl Acetate (CAS 4608-49-5)

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Alternate Names:
(αS,1S,4S,4aS,8aR)-4-(Acetyloxy)-α-ethenyldecahydro-α,5,5,8a-tetramethyl-2-methylene-1-naphthalenepropanol
CAS Number:
4608-49-5
Molecular Weight:
348.52
Molecular Formula:
C22H36O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Larixyl acetate, a derivative of the natural compound larixol found in larch trees, stands as a noteworthy chemical entity in the realm of research, particularly within the field of material science and organic chemistry. Its molecular structure, characterized by an intricate arrangement of carbon, hydrogen, and oxygen atoms, confers upon it unique physicochemical properties that make it an ideal candidate for investigating novel applications in the development of environmentally friendly materials and sustainable chemical processes. The mechanism of action of larixyl acetate revolves around its ability to interact with various organic and inorganic substrates, facilitating the synthesis of complex molecules or enhancing the functional characteristics of materials. This versatility is for researchers aiming to design and synthesize new compounds with specific properties or for those seeking to improve the efficiency and sustainability of chemical reactions. Furthermore, the role of larixyl acetate extends into the exploration of natural product chemistry, offering insights into how plant-derived compounds can be leveraged for the advancement of scientific knowledge and the innovation of green technologies.


Larixyl Acetate (CAS 4608-49-5) References

  1. Mass spectrometric methodology for the analysis of highly oxidized diterpenoid acids in Old Master paintings.  |  Berg, KJ., et al. 2000. J Mass Spectrom. 35: 512-533. PMID: 10797648
  2. Identification of diterpenes in canvas painting varnishes by gas chromatography-mass spectrometry with combined derivatisation.  |  Osete-Cortina, L., et al. 2004. J Chromatogr A. 1024: 187-94. PMID: 14753721
  3. Analytical characterization of diterpenoid resins present in pictorial varnishes using pyrolysis-gas chromatography-mass spectrometry with on line trimethylsilylation.  |  Osete-Cortina, L. and Doménech-Carbó, MT. 2005. J Chromatogr A. 1065: 265-78. PMID: 15782973
  4. Identification and Validation of Larixyl Acetate as a Potent TRPC6 Inhibitor.  |  Urban, N., et al. 2016. Mol Pharmacol. 89: 197-213. PMID: 26500253
  5. Reducing copper use in the environment: the use of larixol and larixyl acetate to treat downy mildew caused by Plasmopara viticola in viticulture.  |  Thuerig, B., et al. 2018. Pest Manag Sci. 74: 477-488. PMID: 28905481
  6. The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction.  |  Chen, X., et al. 2019. J Neuroinflammation. 16: 21. PMID: 30704505
  7. TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-κB activation and ICAM-1 expression with ozone exposure.  |  Chen, QZ., et al. 2019. Exp Cell Res. 377: 56-66. PMID: 30779919
  8. Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.  |  Ortiz-Muñoz, G., et al. 2020. J Clin Invest. 130: 2041-2053. PMID: 31961827
  9. The analgesic action of larixyl acetate, a potent TRPC6 inhibitor, in rat neuropathic pain model induced by spared nerve injury.  |  Wang, J., et al. 2020. J Neuroinflammation. 17: 118. PMID: 32299452
  10. Pharmacological and genetic inhibition of TRPC6-induced gene transcription.  |  Scheuble, J., et al. 2020. Eur J Pharmacol. 886: 173357. PMID: 32758574
  11. New results with regard to the Flora bust controversy: radiocarbon dating suggests nineteenth century origin.  |  Reiche, I., et al. 2021. Sci Rep. 11: 8249. PMID: 33859211
  12. Repurposing Riociguat to Target a Novel Paracrine Nitric Oxide-TRPC6 Pathway to Prevent Podocyte Injury.  |  't Hart, D., et al. 2021. Int J Mol Sci. 22: PMID: 34830371
  13. Characterization of proteinaceous and other organic materials in historical stringed musical instruments by off-line analytical pyrolysis with silylation  |  Alessandro G. Rombolà a, Daniele Fabbri a b, Ryota Shibuya a, Marco Malagodi c d, Tommaso Rovetta c, Giacomo Fiocco c d. 2023. Journal of Analytical and Applied Pyrolysis. 170: 105957.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Larixyl Acetate, 50 mg

sc-488710
50 mg
$344.00