L-Leucine-2-chlorotrityl resin
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L-Leucine-2-chlorotrityl resin is a solid support used in peptide synthesis. Its function is to facilitate the attachment of amino acids during the solid-phase peptide synthesis process. The resin contains a chlorotrityl group that acts as an anchor for the growing peptide chain, allowing for the stepwise addition of amino acids. The mode of action involves the activation of the carboxylic group of the incoming amino acid, which then reacts with the resin-bound amino group to form a peptide bond. This resin is particularly useful for the synthesis of peptides with C-terminal amides, as the chlorotrityl group can be easily removed under mild conditions to reveal the desired peptide product. Overall, L-Leucine-2-chlorotrityl resin plays a crucial role in solid-phase peptide synthesis by providing a solid support for the stepwise assembly of peptide chains.
L-Leucine-2-chlorotrityl resin References
- Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries. | Beyer, BB., et al. 2005. Biochemistry. 44: 1768-79. PMID: 15697202
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Leucine-2-chlorotrityl resin, 1 g | sc-477209 | 1 g | $33.00 | |||
L-Leucine-2-chlorotrityl resin, 5 g | sc-477209A | 5 g | $128.00 |