Date published: 2025-12-14

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L-687,384 hydrochloride

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Alternate Names:
1′-Benzyl-3,4-dihydrospiro[naphthalene-1-(2H),4′-piperidine]
Purity:
≥98%
Molecular Weight:
327.89
Molecular Formula:
C21H25N•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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L-687,384 hydrochloride is a compound that functions as a selective antagonist at the dopamine D1 receptor. It acts by binding to the receptor and blocking the binding of dopamine, thereby inhibiting the activation of downstream signaling pathways. L-687,384 Hydrochloride′s mechanism of action involves targeting the dopamine D1 receptor and interfering with its normal function. By doing so, it modulates the activity of dopaminergic neurotransmission in experimental applications. L-687,384 Hydrochloride′s functional role lies in its ability to selectively block the dopamine D1 receptor, which may be useful for studying the role of this receptor in various physiological and behavioral processes. Its mechanism of action at the molecular level involves disrupting the interaction between dopamine and the receptor, leading to downstream effects on cellular signaling and neurotransmission.


L-687,384 hydrochloride References

  1. An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis.  |  Kälin, RE., et al. 2009. Blood. 114: 1110-22. PMID: 19478043
  2. The identification of inhibitors of Schistosoma mansoni miracidial transformation by incorporating a medium-throughput small-molecule screen.  |  Taft, AS., et al. 2010. Exp Parasitol. 125: 84-94. PMID: 20060828
  3. NU-6027 Inhibits Growth of Mycobacterium tuberculosis by Targeting Protein Kinase D and Protein Kinase G.  |  Kidwai, S., et al. 2019. Antimicrob Agents Chemother. 63: PMID: 31285226

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

L-687,384 hydrochloride, 5 mg

sc-300863
5 mg
$163.00