karyopherin α2 Antibody (8G5): sc-136204

karyopherin α2 Antibody (8G5) is a mouse monoclonal IgG1 kappa light chain antibody that detects karyopherin α2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-karyopherin α2 antibody (8G5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Karyopherin α2 plays a crucial role in the nuclear transport process, specifically in the recognition and import of proteins into the nucleus. Karyopherin α2 is primarily located in the cytoplasm and the nucleus, where karyopherin α2 facilitates the transport of various substrates across the nuclear envelope. Karyopherin α2′s location enables interaction with the nuclear pore complex, ensuring essential proteins are efficiently imported into the nucleus to perform functions, such as gene expression regulation and DNA repair. Karyopherin α2 has been shown to interact with Epstein-Barr virus nuclear antigen 1 (EBNA1), highlighting karyopherin α2′s role in viral pathogenesis and potential implications for understanding viral infections. karyopherin α2 (8G5) monoclonal antibody′s versatility in various applications makes this reagent an invaluable tool for researchers studying nuclear transport mechanisms and related cellular processes.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-karyopherin α2 Antibody (8G5) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-karyopherin α2 Antibody (8G5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

karyopherin α2 Antibody (8G5) Specifications

Alternate Product Name: karyopherin α2

Product Clone Name: 8G5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: karyopherin α2

Epitope Species: human

Product Reactivity/Detection: karyopherin α2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for karyopherin α2 Antibody (8G5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin