raised against full-length recombinant karyopherin α6 of mouse origin
Anti-karyopherin alpha 1/6 Antibody (2D9) is recommended for detection of karyopherin α1 and karyopherin α6 of mouse, rat, human, hamster, bovine and monkey origin by WB, IP, IF and ELISA
karyopherin alpha 1/6 Antibody (2D9) is available conjugated to agarose for IP; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of karyopherin α1/6 (2D9): sc-101540.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
karyopherin α1/6 Antibody (2D9) is a high quality monoclonal karyopherin alpha 1/6 antibody (also designated karyopherin α1/6 antibody) suitable for the detection of the karyopherin alpha 1/6 protein of mouse, rat, human, hamster, bovine and monkey origin. karyopherin α1/6 Antibody (2D9) is available as both the non-conjugated anti-karyopherin alpha 1/6 antibody form, as well as multiple conjugated forms of anti-karyopherin alpha 1/6 antibody, including agarose, PE, FITC and multiple Alexa Fluor® conjugates. Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC). Cytoplasmic proteins that contain nuclear localization signals (NLSs) must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Karyopherin α1 and karyopherin α6 are widely expressed nuclear import proteins that act as adaptors for karyopherin β1, specifically binding to and guiding NLS-containing proteins to the NPC. Both karyopherin α1 and karyopherin α6 contain one IBB domain and ten ARM repeats through which they convey their protein binding and localization function. Together, karyopherin α1 and karyopherin α6 are responsible for ensuring the nuclear import of NLS-containing substrates.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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