Molecular structure of Isofusidienol A, CAS Number: 1032392-18-9
Isofusidienol A (CAS 1032392-18-9)
Application:
Isofusidienol A is an antifungal and antibacterial agent that acts against gram-positive and gram-negative bacteria
CAS Number:
1032392-18-9
Molecular Weight:
300.3
Molecular Formula:
C16H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isofusidienol A functions as an inhibitor of bacterial cell wall synthesis. It exerts its mechanism of action by targeting the translocase I enzyme, which is involved in the peptidoglycan biosynthesis pathway. By inhibiting this enzyme, Isofusidienol A disrupts the formation of the bacterial cell wall, leading to impaired cell growth and division. Isofusidienol A interacts with the active site of translocase I, preventing the binding of substrate molecules and ultimately hindering the synthesis of peptidoglycan. As a result, Isofusidienol A demonstrates the ability to impede the growth and proliferation of certain bacterial strains by interfering with an process in their cell wall formation.
Isofusidienol A (CAS 1032392-18-9) References
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- Marine and terrestrial endophytic fungi: a mine of bioactive xanthone compounds, recent progress, limitations, and novel applications. | Khattab, AR. and Farag, MA. 2022. Crit Rev Biotechnol. 42: 403-430. PMID: 34266351
- Biosynthetic Potential of the Endophytic Fungus Helotiales sp. BL73 Revealed via Compound Identification and Genome Mining. | Oberhofer, M., et al. 2022. Appl Environ Microbiol. 88: e0251021. PMID: 35108081
- Isofusidienols: Novel Chromone-3-oxepines Produced by the Endophytic Fungus Chalara sp. | Sandra Lösgen, Jörg Magull, Barbara Schulz, Siegfried Draeger, Axel Zeeck. 2008. 2008: 698-703.
- Bioactive Potentials of Novel Molecules from the Endophytes of Medicinal Plants | Monnanda S. Nalini, Harischandra S. Prakash & Mysore V. Tejesvi. 2019. Medically Important Plant Biomes: Source of Secondary Metabolites. 293–351.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isofusidienol A, 1 mg | sc-221768 | 1 mg | $200.00 | |||
Isofusidienol A, 5 mg | sc-221768A | 5 mg | $712.00 |